Adam D J, Fitridge R A, Raptis S
University Department of Vascular Surgery, Birmingham Heartlands Hospital, Birmingham, UK.
Eur J Vasc Endovasc Surg. 2005 Nov;30(5):516-9. doi: 10.1016/j.ejvs.2005.05.019. Epub 2005 Jun 21.
Intra-abdominal packing is a valuable adjunct in patients with abdominal trauma and uncontrollable bleeding but few data exist regarding early and late outcome associated with this technique in patients with ruptured abdominal aortic aneurysm (AAA).
Interrogation of a prospective vascular surgical database identified 23 patients (22 men; median age 69, range 59-82, years) with ruptured AAA who required intra-abdominal packing for control of coagulopathic haemorrhage after insertion of an aortic graft between January 1982 and December 2003. Co-morbidity, operative and outcome data were retrieved.
Haemostasis was achieved and packs were removed within 48 h in 20 patients. In those patients who had a graft inserted, the peri-operative mortality rate was 12 of 23 (52%) patients (vs. 172 of 455 (38%) patients who were not packed, NS). Three (13%) patients developed early intra-abdominal sepsis, which was universally fatal: graft-enteric fistula, intra-abdominal abscess with necrotizing fasciitis of the abdominal wound, and infected retroperitoneal haematoma. Two of 11 (18%) survivors developed late graft-related infective complications: major aortic graft infection at 6 months and symptomatic infected para-anastomotic aortic false aneurysm at 39 months. Early and late intra-abdominal infective complications were significantly more common in patients who were packed than in those who were not (packed: five of 23, 22% vs. non-packed: five of 455, 1%; p < 0.001).
These data demonstrate that intra-abdominal packing in coagulopathic patients with ruptured AAA can achieve an acceptable survival rate. However, this technique may be associated with an increased incidence of early and late intra-abdominal infective complications.
腹腔内填塞是腹部创伤且出血无法控制患者的一项重要辅助措施,但关于腹主动脉瘤(AAA)破裂患者应用该技术的早期和晚期结局的数据较少。
查询前瞻性血管外科数据库,确定了1982年1月至2003年12月期间23例(22例男性;中位年龄69岁,范围59 - 82岁)AAA破裂患者,这些患者在植入主动脉移植物后因凝血功能障碍性出血需要腹腔内填塞。检索了合并症、手术及结局数据。
20例患者在48小时内实现止血并取出填塞物。在植入移植物的患者中,围手术期死亡率为23例中的12例(52%)(未行填塞的455例患者中有172例,38%,无显著差异)。3例(13%)患者发生早期腹腔内感染,均死亡:分别为移植物 - 肠瘘、伴有腹部伤口坏死性筋膜炎的腹腔内脓肿以及感染性腹膜后血肿。11例幸存者中有2例(18%)发生晚期移植物相关感染并发症:6个月时发生严重主动脉移植物感染,39个月时发生有症状的吻合口旁主动脉假性动脉瘤感染。腹腔内填塞患者的早期和晚期感染并发症明显比未填塞患者更常见(填塞组:23例中的5例,2%;未填塞组:455例中的5例,1%;p < 0.001)。
这些数据表明,凝血功能障碍的AAA破裂患者进行腹腔内填塞可获得可接受的生存率。然而,该技术可能与早期和晚期腹腔内感染并发症的发生率增加有关。