Becker Stephan T, Vonthein Reinhard, Volpe Nicholas J, Schiefer Ulrich
Department of Pathophysiology of Vision and Neuro-Ophthalmology, University Eye Hospital, Tübingen, Germany.
Invest Ophthalmol Vis Sci. 2005 Jul;46(7):2633-8. doi: 10.1167/iovs.04-1413.
To determine the effect of age, examination, location, luminance, subject, and vigilance on reaction time (RT) in automated kinetic perimetry.
Thirty-six normal volunteers (20-70 years old) underwent kinetic campimetric examinations, during which RTs (time from appearance of a stimulus to response) were recorded. Stimuli with a diameter of 26 minutes of arc (Goldmann III) were presented on horizontal vectors with an angular velocity of 2 deg/s. Thirty-two positions in the 30 degrees radius visual field were tested six times, at luminance levels of 41.62 and 110 cd/m2 (background 10 cd/m2). An analysis of RT variance (ANCOVA) was performed.
Median RT increased with age from 370 ms (20-30-year-old subjects) to 440 ms (60-70-year-old subjects). There was a strong dependency of RT from the individual subjects examined (means range, 313-411 ms), from the course of one examination period, from the examination and stimulus luminance, and from the location in the visual field.
Reaction time during automated kinetic perimetry varies considerably. This study shows that the factors of age, the subject examined, his or her daily condition, the course within one examination period, and the stimulus location and luminance are of relevance. For a much more reliable prediction of individual RTs and thus a precise assessment of local kinetic thresholds, application of some additional kinetic stimuli (RT time vectors) within the intact visual field areas is necessary.
确定年龄、检查、位置、亮度、受试者和警觉性对自动动态视野检查中反应时间（RT）的影响。
36名正常志愿者（20 - 70岁）接受了动态视野检查，在此期间记录反应时间（从刺激出现到反应的时间）。直径为26分视角（戈德曼III）的刺激以2度/秒的角速度呈现在水平向量上。在半径30度视野中的32个位置，在亮度水平为41.62和110 cd/m²（背景10 cd/m²）的情况下进行了6次测试。进行了反应时间方差分析（协方差分析）。
平均反应时间随年龄从370毫秒（20 - 30岁受试者）增加到440毫秒（60 - 70岁受试者）。反应时间强烈依赖于所检查的个体受试者（平均值范围为313 - 411毫秒）、一个检查期的过程、检查和刺激亮度以及视野中的位置。
自动动态视野检查期间的反应时间变化很大。本研究表明，年龄、被检查的受试者、其日常状况、一个检查期内的过程以及刺激位置和亮度等因素具有相关性。为了更可靠地预测个体反应时间，从而精确评估局部动态阈值，有必要在完整视野区域内应用一些额外的动态刺激（反应时间向量）。
