德国儿科患者化脓性链球菌分离株中红霉素耐药性与纤连蛋白结合蛋白F1基因（prtF1）存在之间的关联。
Association between resistance to erythromycin and the presence of the fibronectin binding protein F1 gene, prtF1, in Streptococcus pyogenes isolates from German pediatric patients.
作者信息
Haller Maria, Fluegge Kirsten, Arri Sandra Jasminder, Adams Brit, Berner Reinhard
机构信息
Department of Pediatrics and Adolescent Medicine, University Hospital of Freiburg, Mathildenstrasse 1, 79106 Freiburg, Germany.
出版信息
Antimicrob Agents Chemother. 2005 Jul;49(7):2990-3. doi: 10.1128/AAC.49.7.2990-2993.2005.
Abstract
A total of 301 German pediatric group A streptococcus isolates were screened for the presence of macrolide resistance and the fibronectin binding protein F1 gene (prtF1) encoding an adhesin and cell invasiveness protein. The prtF1 gene was present significantly more often among macrolide-resistant isolates. The majority of these were not clonally related.
摘要
共对301株德国A组链球菌儿科分离株进行了大环内酯类耐药性以及编码粘附素和细胞侵袭蛋白的纤连蛋白结合蛋白F1基因（prtF1）的筛查。prtF1基因在大环内酯类耐药分离株中出现的频率明显更高。其中大多数并非克隆相关。
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