来自多杀性巴氏杆菌的新型壮观霉素/链霉素抗性基因aadA14。
Novel spectinomycin/streptomycin resistance gene, aadA14, from Pasteurella multocida.
作者信息
Kehrenberg Corinna, Catry Boudewijn, Haesebrouck Freddy, de Kruif Aart, Schwarz Stefan
机构信息
Institut für Tierzucht, Bundesforschungsanstalt für Landwirtschaft (FAL), Höltystr. 10, 31535 Neustadt-Mariensee, Germany.
出版信息
Antimicrob Agents Chemother. 2005 Jul;49(7):3046-9. doi: 10.1128/AAC.49.7.3046-3049.2005.
Abstract
A novel spectinomycin/streptomycin resistance gene, designated aadA14, was detected on the mobilizable 5,198-bp plasmid pCCK647 from Pasteurella multocida. The aadA14 gene encodes an aminoglycoside adenylyltransferase of 261 amino acids. Sequence comparisons revealed that the AadA14 protein showed less than 60% identity to the AadA proteins known so far.
摘要
在多杀性巴氏杆菌可移动的5198 bp质粒pCCK647上检测到一个新的壮观霉素/链霉素抗性基因，命名为aadA14。aadA14基因编码一个由261个氨基酸组成的氨基糖苷腺苷酸转移酶。序列比较显示，AadA14蛋白与目前已知的AadA蛋白的同一性低于60%。
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