斯洛伐克一家医院产超广谱β-内酰胺酶肠杆菌科细菌的调查：SHV-2a的优势及TEM-132的特征分析
Survey of Enterobacteriaceae producing extended-spectrum beta-lactamases in a Slovak hospital: dominance of SHV-2a and characterization of TEM-132.
作者信息
Zarnayová Martina, Siebor Eliane, Péchinot André, Duez Jean-Marie, Bujdáková Helena, Labia Roger, Neuwirth Catherine
机构信息
Laboratoire de Bactériologie, Hôpital Universitaire du Bocage, BP 77908, 21079 Dijon Cedex, France.
出版信息
Antimicrob Agents Chemother. 2005 Jul;49(7):3066-9. doi: 10.1128/AAC.49.7.3066-3069.2005.
Abstract
Eighty-five extended-spectrum beta-lactamase-producing Enterobacteriaceae from a Slovak hospital have been studied. SHV-2a was predominant, but other variants have been detected, namely, SHV-5, SHV-12, TEM-12, TEM-15, and TEM-132, which differed from TEM-1 by amino acid substitutions R164H, E240K, and I173V and had kinetic properties similar to those of TEM-28.
摘要
对斯洛伐克一家医院的85株产超广谱β-内酰胺酶肠杆菌科细菌进行了研究。SHV-2a占主导地位，但也检测到了其他变体，即SHV-5、SHV-12、TEM-12、TEM-15和TEM-132，它们与TEM-1的区别在于氨基酸替换R164H、E240K和I173V，并且具有与TEM-28相似的动力学特性。
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