[腹腔镜胆囊切除术中医源性胆道损伤的预防、诊断与治疗。侵入性内镜检查后乳头损伤的处理。第1部分。胆管损伤的预防与诊断]
[Prevention, diagnosis and treatment of iatrogennic lesions of biliary tract during laparoscopic cholecystectomy. Management of papila injury after invasive endoscopy. Part 1. Prevention and diagnosis of bile duct injuries].
作者信息
Sváb J, Pesková M, Krska Z, Gürlich R, Kasalický M
机构信息
I. chirurgická klinika 1. LF UK a VFN v Praze.
出版信息
Rozhl Chir. 2005 Apr;84(4):176-81.
INTRODUCTION
Endoscopic invasive procedures in 70th and 80th years leaded to decrease reoperations on biliary tree. Iatrogenic injury of the biliary tract have increased in incidence in the first decade with the introduction of laparoscopic cholecystectomy. Athough a number of factors have been identified with a high risk of injury ( and number of technical steps have been emphasized to avoid these injury, the incidence of the bile duct injury has reached at least double the rate observed with open cholecystectomy. Cholecystectomy is most frequently performed abdominal operation and the most serious complication associated with this procedure is accidental injury to the common bile duct (0.3-0.4%). This preventable technical error has tradicionally been thought to occur in one or more of three situations: 1. When the operator attempts to clip or ligate a bleeding cystic artery and also clips the common hepatic duct (Fig. 3a). 2. When too much traction has been exerted on the gallbladder so that the common bile duct has tented up into an albow, which was either tied off with ligature or clipped (Fig. 3b). 3. When anatomic anomalies were not recognized and the wrong structure is divided, for example, when the cystic duct winds anterior to the common bile duct and enters on the left side, or when the cystic duct joins the right hepatic duct rather than the junction of the common hepatic and the common bile ducts (Fig. 1, 2, 3cd). In anatomical incertain cases is discussed about cholangiography and cholecystocholangiography during laparoscopy cholecystectomy. Most patients sustained a bile duct injury are recognized in the weeks folloving laparoscopic cholecystectomy. Careful preoperative preparation should include control of sepsis by draining any bile collections or fistulas and komplete cholangiography. Long-term results are best achieved in specialized hepatobiliary centres performing biliary reconstruction with a Roux-Y hepaticojejunostomy. Success rates over 90% have been reported from several centres to date with intermediate follow-up. Papila injury increased with introduction of a invasive endoscopy. Risk of deadly retroperitoneal inflamation is very high. Injury require same surgery procedure as duodenum injury.
OWN EXPERIENCES
In an article a review of experiences of the 1st surgery department of General hospital in Prague since 1971 in 1 017 reoperations on biliary tree was carried out. There was in 311 patients 164 hepatohepatostomies and 147 hepaticojejunostomies used (Tab. 1). By laparoscopic injuries were high hilar injuries (Bismuth IV) in last decade and hepaticojejunostomy was done in all cases. Died 6%, long term results are acceptable by injured patients with hepaticohepaticostomies in 70%, by hepaticojejunostomies in 90%. Reoperated were 10% patients (Tab. 1). Remnant patients were dilated endoscopicaly. Postoperatively morbidity was high, above 26%. In years 1995-2003 were 8 patients with papila injury and inflamation in retroperitoneum operated as a injured duodenum (Tab. 2).
CONCLUSIONS
Better experiences with treatment of injured biliary tree and papila are in centres interested in hepatobilliary surgery which knowledge anatomy of hilus of liver and can make wide hepaticojejunostomy. Transfer of drained injured patient to centre is possible.
引言
20世纪70年代和80年代的内镜侵入性手术减少了胆道再次手术的次数。随着腹腔镜胆囊切除术的引入,在第一个十年中,医源性胆道损伤的发生率有所增加。尽管已经确定了许多具有高损伤风险的因素(并且强调了许多技术步骤以避免这些损伤),但胆管损伤的发生率至少达到了开腹胆囊切除术观察到的发生率的两倍。胆囊切除术是最常进行的腹部手术,与此手术相关的最严重并发症是意外损伤胆总管(0.3 - 0.4%)。传统上认为这种可预防的技术错误发生在以下三种或更多情况中:1. 当操作者试图夹闭或结扎出血的胆囊动脉时,也夹闭了肝总管(图3a)。2. 当对胆囊施加过多牵引力时,胆总管向上形成一个弯头,用结扎线结扎或夹闭(图3b)。3. 当未识别解剖异常并切断了错误的结构时,例如,当胆囊管在胆总管前方蜿蜒并从左侧进入时,或者当胆囊管连接右肝管而不是肝总管与胆总管的交界处时(图1、2、3c - d)。在解剖情况不确定的病例中,讨论了腹腔镜胆囊切除术中的胆管造影和胆囊胆管造影。大多数遭受胆管损伤的患者在腹腔镜胆囊切除术后数周内被识别出来。仔细的术前准备应包括通过引流任何胆汁积聚或瘘管以及完成胆管造影来控制感染。在进行Roux - Y肝空肠吻合术进行胆道重建的专业肝胆中心可获得最佳的长期结果。迄今为止,几个中心报告的中期随访成功率超过90%。随着侵入性内镜检查的引入,乳头损伤增加。致命性腹膜后炎症的风险非常高。损伤需要与十二指肠损伤相同的手术程序。
自身经验
在一篇文章中,对布拉格综合医院第一外科自1971年以来对胆道进行的1017次再次手术的经验进行了回顾。311例患者中,使用了164例肝肝吻合术和147例肝空肠吻合术(表1)。在过去十年中,腹腔镜损伤为高位肝门损伤(Bismuth IV型),所有病例均进行了肝空肠吻合术。死亡率为6%,肝肝吻合术损伤患者的长期结果70%可接受,肝空肠吻合术损伤患者的长期结果90%可接受。10%的患者再次手术(表1)。其余患者通过内镜扩张。术后发病率很高,超过26%。1995年至2003年期间,8例乳头损伤和腹膜后炎症患者作为十二指肠损伤进行了手术(表2)。
结论
在对肝脏肝门解剖结构有了解且能进行广泛肝空肠吻合术的肝胆外科感兴趣的中心,对受损胆道和乳头的治疗有更好的经验。将引流后的受伤患者转移到中心是可行的。