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通过调节新陈代谢来延长寿命。为了使人类健康和寿命最大化,科学家们必须摒弃过时的微量营养素模型。

Increasing longevity by tuning up metabolism. To maximize human health and lifespan, scientists must abandon outdated models of micronutrients.

作者信息

Ames Bruce N

机构信息

The Children's Hospital Oakland Research Institute, Oakland, CA, USA.

出版信息

EMBO Rep. 2005 Jul;6 Spec No(Suppl 1):S20-4. doi: 10.1038/sj.embor.7400426.

Abstract

To maximize human health and lifespan, scientists must abandon outdated models of micronutrients

摘要

为了最大化人类健康和寿命,科学家们必须摒弃过时的微量营养素模型。

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本文引用的文献

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3
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Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):11153-8. doi: 10.1073/pnas.0404349101. Epub 2004 Jul 19.
4
Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress.
Curr Med Chem. 2004 May;11(9):1135-46. doi: 10.2174/0929867043365387.
5
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid.
Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3381-6. doi: 10.1073/pnas.0400282101. Epub 2004 Feb 25.
9
Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line.
Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16770-5. doi: 10.1073/pnas.222679399. Epub 2002 Dec 12.
10
Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging.
Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14807-12. doi: 10.1073/pnas.192585799. Epub 2002 Nov 4.

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