Ko Gary Tin-Choi, Cockram Clive Stewart, Chow Chun-Chung, Yeung Vincent, Chan Wing-Bun, So Wing-Yee, Chan Norman Nor, Chan Juliana Chun-Ngor
Department of Medicine, AH Nethersole Hospital, Tai Po, Hong Kong.
Diabetes Res Clin Pract. 2005 Aug;69(2):160-8. doi: 10.1016/j.diabres.2004.11.015. Epub 2005 Jan 21.
The World Health Organisation (WHO), European Group for the Study of Insulin Resistance (EGIR) and National Cholesterol Education Program (NCEP) Expert Panels had introduced definitions for the metabolic syndrome (MES). We aimed to estimate the prevalence of MES in a working population in Hong Kong using the three definitions for MES and compare their relative significance. The data are obtained from a prevalence survey for glucose intolerance and lipid abnormality in a Hong Kong Chinese working population. The distribution of occupational groups in these subjects was similar to that recorded in the Hong Kong Census (1991) and representative of the Hong Kong working population. Definition of obesity was modified using the Asian criterion of body mass index (BMI)> or =25 kg/m 2, waist circumference>80 cm in women and >90 cm in men. Of the 1513 subjects, 910 (60.1%) were men and 603 (39.9%) were women. The mean age was 37.5+/-9.2 (median 37.0 years, range 18-66 years). Using the Asian definition for obesity, the prevalence of MES using the WHO criterion was the highest (WHO versus EGIR versus NCEP-overall: 13.4% versus 8.9% versus 9.6%, p<0.001; under age of 40 years: 7.9% versus 4.9% versus 5.4%, p=0.017; age of 40 years or above: 21.9% versus 14.9% versus 16.0%, p=0.003). The prevalence of different components of the MES ranged from 6 to 38%. In subjects aged less than 50 years, there was a male preponderance for MES (male versus female-WHO: 9.5% versus 6.2%, p=0.007; EGIR: 7.9% versus 6.2%, p=0.235; NCEP: 9.5% versus 6.2%, p=0.030) but this trend was reversed after the age of 50 years (WHO: 29.3% versus 31.9%, p=0.721; EGIR: 13.1% versus 34.8%, p=0.001; NCEP: 19.2% versus 23.2%, p=0.533). The prevalence of MES in Hong Kong Chinese of working age ranges from 6.1 to 13.4% depending on various diagnostic criteria. There was a male preponderance before the age of 50 years and a female-preponderance after the age of 50 years. The inclusion of albuminuria and insulin resistance by the WHO has made it the most discriminative criterion in identifying at risk individuals in all age groups.
世界卫生组织（WHO）、欧洲胰岛素抵抗研究小组（EGIR）以及美国国家胆固醇教育计划（NCEP）专家小组已引入了代谢综合征（MES）的定义。我们旨在使用MES的三种定义来估算香港在职人群中MES的患病率，并比较它们的相对重要性。数据来自一项针对香港在职华人群体中葡萄糖不耐受和脂质异常的患病率调查。这些受试者的职业群体分布与香港人口普查（1991年）记录的相似，代表了香港在职人群。肥胖的定义采用亚洲标准，即体重指数（BMI）≥25kg/m²，女性腰围>80cm，男性腰围>90cm。在1513名受试者中，910名（60.1%）为男性，603名（39.9%）为女性。平均年龄为37.5±9.2岁（中位数37.0岁，范围18 - 66岁）。采用亚洲肥胖定义，使用WHO标准时MES的患病率最高（WHO与EGIR与NCEP - 总体：13.4%对8.9%对9.6%，p<0.001；40岁以下：7.9%对4.9%对5.4%，p = 0.017；40岁及以上：21.9%对14.9%对16.0%，p = 0.003）。MES不同组分的患病率在6%至38%之间。在年龄小于50岁的受试者中，MES存在男性优势（男性对女性 - WHO：9.5%对6.2%，p = 0.007；EGIR：7.9%对6.2%，p = 0.235；NCEP：9.5%对6.2%，p = 0.030），但50岁以后这种趋势逆转（WHO：29.3%对31.9%，p = 0.721；EGIR：13.1%对34.8%，p = 0.001；NCEP：19.2%对23.2%，p = 0.533）。根据不同诊断标准，香港在职华人群体中MES的患病率在6.1%至13.4%之间。50岁之前男性占优势，50岁之后女性占优势。WHO纳入蛋白尿和胰岛素抵抗使其成为在所有年龄组中识别高危个体最具鉴别力的标准。
