Osei-Yeboah James, Owiredu William K B A, Norgbe Gameli Kwame, Yao Lokpo Sylvester, Gyamfi Jones, Alote Allotey Emmanuel, Asumbasiya Aduko Romeo, Noagbe Mark, Attah Florence A
Department of Medical Laboratory Sciences, School of Allied Health Sciences, University of Health and Allied Sciences, Ho, Ghana.
Department of Molecular Medicine, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; Department of Clinical Biochemistry, Diagnostic Directorate, Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Int J Chronic Dis. 2017;2017:8765804. doi: 10.1155/2017/8765804. Epub 2017 Feb 12.
The cooccurrence of diabetes mellitus and metabolic syndrome potentiates the cardiovascular risk associated with each of the conditions; therefore characterizing metabolic syndrome among people with type 2 diabetes is beneficial for the purpose of cardiovascular disease prevention. This study aims at evaluating the prevalence of metabolic syndrome and its components among 162 patients with type 2 diabetes attending the diabetic clinic of the Ho Municipal Hospital, Ghana. Data obtained included anthropometric indices, blood pressure, serum lipids, glucose, and sociodemographics and clinical information. The overall prevalence of metabolic syndrome among the study population was 43.83%, 63.58%, and 69.14% using the NCEP-ATP III, the WHO, and the IDF criteria, respectively. The most predominant component among the study population was high blood pressure using the NCEP-ATP III (108 (66.67%)) and WHO (102 (62.96)) criteria and abdominal obesity (112 (69.14%)) for IDF criteria. High blood pressure was the most prevalent component among the males while abdominal obesity was the principal component among the females. In this population with type 2 diabetes, high prevalence of metabolic syndrome exists. Gender vulnerability to metabolic syndrome and multiple cluster components were skewed towards the female subpopulation with type 2 diabetes.
糖尿病和代谢综合征并存会增加与每种病症相关的心血管风险；因此，对2型糖尿病患者的代谢综合征进行特征描述，对于预防心血管疾病是有益的。本研究旨在评估加纳霍市立医院糖尿病门诊的162例2型糖尿病患者中代谢综合征及其组成成分的患病率。获得的数据包括人体测量指标、血压、血脂、血糖以及社会人口统计学和临床信息。分别采用美国国家胆固醇教育计划成人治疗组第三次报告（NCEP-ATP III）、世界卫生组织（WHO）和国际糖尿病联盟（IDF）标准，研究人群中代谢综合征的总体患病率分别为43.83%、63.58%和69.14%。按照NCEP-ATP III标准（108例（66.67%））和WHO标准（102例（62.96%）），研究人群中最主要的组成成分是高血压；按照IDF标准，最主要的组成成分是腹型肥胖（112例（69.14%））。高血压是男性中最普遍的组成成分，而腹型肥胖是女性中的主要组成成分。在这个2型糖尿病患者群体中，代谢综合征的患病率很高。2型糖尿病女性亚群体在代谢综合征和多种聚类成分方面的性别易感性存在偏差。
