Department of Oral and Maxillofacial Surgery, Kings County Hospital Center, Brooklyn, NY, USA.
Department of General Surgery, Kings County Hospital Center, Brooklyn, NY, USA.
Am J Case Rep. 2021 Mar 26;22:e928999. doi: 10.12659/AJCR.928999.
BACKGROUND Cutaneous metastasis of renal cell carcinoma is exceedingly rare, and there are few described cases of metastasis to the skin of the head and neck region. Most of these cases describe metastases to the scalp, but some cases of metastases to the face and neck have been reported. CASE REPORT A 72-year-old man presented to the Surgery Clinic with a chief complaint of a lesion that had grown on his left cheek over a period of about 3 months. A punch biopsy revealed the mass to be metastatic renal cell carcinoma, clear-cell subtype. The patient had already had a nephrectomy for primary tumor control. Due to the advanced disease process, the patient elected for palliative care. CONCLUSIONS Cutaneous presentations of renal cell carcinoma in the head and neck are exceptionally rare, and metastases to the face are less common than metastases to the scalp. When this disease process does occur, it often presents as a raised mass of between 1 and 3 cm with a red, red-purple, or red-blue color. Patient history often reveals a relatively rapid growth process of their facial lesion. This case highlights the fact that malignancies may manifest several years after initial primary resection.
肾细胞癌皮肤转移极为罕见，且鲜有头颈部皮肤转移的病例描述。这些病例多数描述的是头皮转移，但也有一些面部和颈部转移的病例报道。
一名 72 岁男性因左脸颊上的一个肿物在大约 3 个月内逐渐增大而就诊于外科诊所。经皮肤活检，该肿物被诊断为转移性肾细胞癌，透明细胞亚型。患者曾因控制原发性肿瘤而接受过肾切除术。由于疾病进展已处于晚期，患者选择接受姑息治疗。
头颈部肾细胞癌的皮肤表现极为罕见，且面部转移比头皮转移更为少见。当这种疾病发生时，通常表现为直径在 1 至 3 厘米之间的高出皮肤的红色、红紫色或红蓝相间的肿块。患者病史常提示其面部病变的生长过程较快。本例强调了这样一个事实，即恶性肿瘤可能在初次原发性切除术后数年才会出现。
