在临床实验室环境中检测阴道样本中的念珠菌属。
Detection of Candida species in vaginal samples in a clinical laboratory setting.
作者信息
Trama Jason P, Adelson Martin E, Raphaelli Israel, Stemmer Shlomo M, Mordechai Eli
机构信息
Medical Diagnostic Laboratories, L.L.C, Hamilton, NJ 08690, USA.
出版信息
Infect Dis Obstet Gynecol. 2005 Jun;13(2):63-7. doi: 10.1080/10647440400025629.
OBJECTIVE
To present the detection rates of Candida species in vaginal samples from patients visiting physicians.
METHODS
The presence of C. albicans, C. glabrata, C. parapsilosis and C. tropicalis in 3978 vaginal swabs from patients in six US states was detected by PCR amplification.
RESULTS
Candida DNA was detected in 33.1% of the population studied. Of the 1316 positive samples, 80.2% contained C. albicans, 14.3% contained C. glabrata, 5.9% contained C. parapsilosis and 8.0% contained C. tropicalis. Comparing samples by patients' state of residence revealed an association with the detection of C. glabrata (p = 0.029). Comparing samples by patients' age revealed a decrease in the overall detection of Candida (p < 0.001) and C. albicans (p < 0.001), concomitant with an increase in the detection of C. glabrata (p < 0.001) and C. parapsilosis (p = 0.025).
CONCLUSIONS
These results provide geographic- and age-specific data on four Candida species associated with vaginitis.
目的
呈现就诊患者阴道样本中念珠菌属的检出率。
方法
通过聚合酶链反应（PCR）扩增检测美国六个州3978例患者阴道拭子中白色念珠菌、光滑念珠菌、近平滑念珠菌和热带念珠菌的存在情况。
结果
在所研究的人群中，33.1%检测到念珠菌DNA。在1316份阳性样本中，80.2%含有白色念珠菌，14.3%含有光滑念珠菌，5.9%含有近平滑念珠菌，8.0%含有热带念珠菌。按患者居住州比较样本发现与光滑念珠菌的检出存在关联（p = 0.029）。按患者年龄比较样本发现念珠菌总体检出率（p < 0.001）和白色念珠菌检出率（p < 0.001）下降，同时光滑念珠菌（p < 0.001）和平滑念珠菌（p = 0.025）检出率增加。
结论
这些结果提供了与阴道炎相关的四种念珠菌属的地理和年龄特异性数据。
Zotero 插件