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[全身性肌腱病]

[Generalized tendomyopathy].

作者信息

Brückle W

机构信息

Rheumaklinik Sonnengarten.

出版信息

Fortschr Med. 1992 May 20;110(14):251-7.

PMID:1601371
Abstract

Generalised tendomyopathy (fibromyalgia) is characterised by diffuse localized pain involving the locomotory system, tenderness in the regions of the tendon insertions and muscles, loss of muscular power, sleep disorders and other vegetative functional and psychological disorders. In many cases, the diagnosis is delayed, often being made only after comprehensive superfluous diagnostic procedures, sometimes invasive, and inappropriate treatment. Age at disease onset is about 35 years, and initially involves, usually localized, the cervical or lumbar region of the spine. The condition is usually progressive over years. Pathogenesis is multifactorial; for generalization and persistence of the disease, psychosocial factors and civilization-related phenomena appear to play a decisive role. Treatment of generalized tendomyopathy is, for the most part, symptomatic and, overall, unsatisfactory. By way of medical treatment, only antidepressants seem to have a certain positive effect in some of the patients. Of importance is a good doctor--patient relationship and successful motivation of the patient to undergo active physiotherapeutic--in some cases also psychotherapeutic--treatment. With an eye to instituting more successful therapeutic measures and avoiding unnecessary diagnostic and therapeutic procedures, and, last but not least, for socioeconomic reasons, early diagnosis is of great importance.

摘要

广泛性肌腱病(纤维肌痛)的特征是涉及运动系统的弥漫性局部疼痛、肌腱附着点和肌肉区域压痛、肌肉力量丧失、睡眠障碍以及其他自主神经功能和心理障碍。在许多情况下,诊断会延迟,通常只有在进行了全面的、有时是侵入性的多余诊断程序和不适当的治疗之后才能做出诊断。发病年龄约为35岁,最初通常累及脊柱的颈部或腰部区域,且通常是局部性的。这种情况通常会在数年内逐渐发展。发病机制是多因素的;对于疾病的扩散和持续存在,社会心理因素和与文明相关的现象似乎起着决定性作用。广泛性肌腱病的治疗大多是对症治疗,总体效果并不理想。在药物治疗方面,似乎只有抗抑郁药对一些患者有一定的积极作用。良好的医患关系以及成功激发患者积极接受物理治疗(在某些情况下还包括心理治疗)非常重要。为了制定更成功的治疗措施,避免不必要的诊断和治疗程序,以及最重要的是出于社会经济原因,早期诊断至关重要。

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