Suess R P, Barr S C, Sacre B J, French T W
Department of Small Animal Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
J Am Vet Med Assoc. 1992 May 1;200(9):1346-8.
Bone marrow hypoplasia and feminization developed in a 10-year-old male German Shepherd Dog with interstitial cell tumor. Clinical abnormalities included pyrexia, pale mucous membranes, signs of abdominal pain, large left testis, atrophied right testis, and feminization. Abnormal laboratory findings included pancytopenia, bacteremia, bacteriuria, and pyuria. Results of cytologic examination of a bone marrow aspirate were consistent with aplastic anemia. Serum estradiol concentration was high, and serum testosterone concentration was low, compared with normal values for male dogs. The left testicular mass was identified as an interstitial cell tumor. Other causes of the aplastic anemia or feminization were not found.
一只10岁的雄性德国牧羊犬患间质细胞瘤，出现了骨髓发育不全和雌性化症状。临床异常表现包括发热、黏膜苍白、腹痛体征、左侧睾丸肿大、右侧睾丸萎缩以及雌性化。实验室检查异常结果包括全血细胞减少、菌血症、菌尿症和脓尿。骨髓穿刺液的细胞学检查结果与再生障碍性贫血相符。与雄性犬的正常值相比，血清雌二醇浓度升高，血清睾酮浓度降低。左侧睾丸肿块被确定为间质细胞瘤。未发现再生障碍性贫血或雌性化的其他病因。
