Schäfer V, Shah P M, Doerr H W, Ziemen M, Hellwich S, Seibert G
Johann Wolfgang Goethe University Hospital, Frankfurt, Germany.
J Antimicrob Chemother. 1992 Apr;29 Suppl A:7-12. doi: 10.1093/jac/29.suppl_a.7.
The in-vitro activity of cefpirome, a new injectable cephalosporin, was compared with that of several other antibiotics against bacterial isolates from hospitalized patients with lower respiratory tract infections, urinary tract infections and wound infections. Minimum inhibitory concentrations were determined for 874 strains against 16 antibiotics using a microtitration technique. Cefpirome showed a very broad spectrum of activity against most pathogens tested. The spectrum included organisms such as Staphylococcus spp., enterococci, Enterobacter spp., and Pseudomonas spp. which are frequently resistant to third generation cephalosporins.
将一种新型注射用头孢菌素头孢匹罗的体外活性与其他几种抗生素针对来自患有下呼吸道感染、尿路感染和伤口感染的住院患者的细菌分离株的活性进行了比较。使用微量滴定技术测定了874株菌株对16种抗生素的最低抑菌浓度。头孢匹罗对大多数测试病原体显示出非常广谱的活性。该谱包括葡萄球菌属、肠球菌、肠杆菌属和假单胞菌属等通常对第三代头孢菌素耐药的微生物。
