Wannamethee S Goya, Ebrahim Shah, Papacosta Olia, Shaper A Gerald
Department of Primary Care and Population Science, Royal Free and University College Medical School, London NW3 2PF, UK.
J Clin Epidemiol. 2005 Aug;58(8):831-40. doi: 10.1016/j.jclinepi.2005.01.007.
We have examined predictors of the onset of and recovery from mobility limitation and the association between lifestyle changes in later life and mobility status.
From a cohort of 7,735 men recruited at ages 40-59 years (1978-1980), 5,075 men completed follow-up postal questionnaires in 1992 (Q92), then aged 52-73 years, and again in 1996 (Q96). Mobility limitation was defined as reported difficulty in any one or more of the following: getting outdoors, walking 400 yards, or climbing stairs.
Lifestyle factors (smoking, obesity, physical inactivity, and heavy drinking) and manual worker social class were significantly and independently associated with onset of mobility limitation and with the exception of physical activity remained significant after further adjustment for chronic diseases. Smoking cessation and taking up physical activity in later life are associated with reduced onset of mobility limitation. Among men with mobility limitation at Q92 (n=645), light or moderate levels of physical activity were associated with significantly increased odds of recovery at Q96 (light activity, OR=2.43, 95% CI 1.48, 4.00; moderate activity, OR=2.57, 95% CI 1.31, 5.02).
Maintaining and adopting a healthy lifestyle in later life reduces the onset of mobility limitation in old age. Maintaining physical activity may improve recovery.
我们研究了行动能力受限的发病及恢复的预测因素,以及晚年生活方式变化与行动能力状态之间的关联。
从1978 - 1980年招募的7735名40 - 59岁男性队列中,5075名男性在1992年(问卷92)完成了随访邮寄问卷,当时年龄为52 - 73岁,并于1996年(问卷96)再次完成问卷。行动能力受限定义为报告在以下任何一项或多项活动中有困难:外出、行走400码或爬楼梯。
生活方式因素(吸烟、肥胖、缺乏身体活动和大量饮酒)以及体力劳动者社会阶层与行动能力受限的发病显著且独立相关,除身体活动外,在进一步调整慢性疾病后仍具有显著性。晚年戒烟和开始进行身体活动与行动能力受限发病的减少相关。在问卷92时行动能力受限的男性(n = 645)中,轻度或中度身体活动水平与问卷96时恢复几率显著增加相关(轻度活动,OR = 2.43,95%CI 1.48,4.00;中度活动,OR = 2.57,95%CI 1.31,5.02)。
晚年保持和采用健康的生活方式可减少老年行动能力受限的发病。保持身体活动可能会改善恢复情况。