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非常小的气泡(10 - 70微升)会导致注射泵液体输送出现临床上显著的变异性。

Very small air bubbles (10 - 70 microl) cause clinically significant variability in syringe pump fluid delivery.

作者信息

Davey C, Stather-Dunn T

机构信息

Bath INstitute of Medical Engineering, The Wolfson Centre, Royal United Hospital, Combe Park, Bath, UK.

出版信息

J Med Eng Technol. 2005 May-Jun;29(3):130-6. doi: 10.1080/03091900500067801.

DOI:10.1080/03091900500067801
PMID:16019882
Abstract

AIM

The goal of this study was to analyse flow disturbances resulting from the presence of small air bubbles in syringe pump delivery lines incorporating pressure-sensing discs.

METHODS

Laboratory based gravimetric measurement of syringe pump flow rate with concurrent fluid pressure monitoring.

RESULTS

Small air bubbles can become lodged in the pressure-sensing disc part of syringe pump delivery lines. This can give rise to serious disturbances in fluid delivery from minute to minute, but does not trigger pump alarms. Small air bubbles being delivered through non-horizontal sections of delivery line can also cause significant transient disturbances to fluid delivery.

CONCLUSIONS

The demonstrated disruptions to fluid delivery could be sufficient to cause adverse effects on patients, particularly in the case of a vulnerable patient receiving a potent fast-acting drug at a low flow rate. The prevalence of these effects in clinical settings would be difficult to establish, but careful efforts to remove air from syringe delivery lines before starting infusions would be recommended to minimize the risks.

摘要

目的

本研究的目的是分析在装有压力传感盘的注射泵输送管路中,小气泡的存在所导致的流量干扰。

方法

基于实验室的重量法测量注射泵流速,并同时监测流体压力。

结果

小气泡可能会滞留在注射泵输送管路的压力传感盘部分。这可能会导致每分钟的流体输送出现严重干扰,但不会触发泵的警报。通过输送管路非水平部分输送的小气泡也会对流体输送造成显著的瞬时干扰。

结论

已证明的流体输送中断可能足以对患者造成不良影响,特别是对于脆弱患者以低流速接受强效速效药物的情况。这些影响在临床环境中的发生率难以确定,但建议在开始输液前仔细努力清除注射器输送管路中的空气,以将风险降至最低。

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Very small air bubbles (10 - 70 microl) cause clinically significant variability in syringe pump fluid delivery.非常小的气泡(10 - 70微升)会导致注射泵液体输送出现临床上显著的变异性。
J Med Eng Technol. 2005 May-Jun;29(3):130-6. doi: 10.1080/03091900500067801.
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[Factors altering low-flow drug delivery using syringe pumps: Consequences on vasoactive drug infusion in preterm infant].[使用注射泵改变低流量药物输送的因素:对早产儿血管活性药物输注的影响]
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