Elston J S
National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.
J Neurol Neurosurg Psychiatry. 1992 May;55(5):369-71. doi: 10.1136/jnnp.55.5.369.
Ten patients who were unable to initiate or sustain eye opening in the absence of overt spasm of the orbicularis oculi, were investigated. In five, the problem was isolated. Three had Parkinson's disease and two progressive supra-nuclear palsy for between one to six years before the eye opening difficulty developed. The clinical features and electrophysiological investigation suggested that the disorder is a variant of blepharospasm due to abnormal contraction in the pre-tarsal orbicularis oculi.
对10例在无明显眼轮匝肌痉挛时无法睁眼或维持睁眼的患者进行了研究。其中5例问题为孤立性。3例患有帕金森病,2例患有进行性核上性麻痹,在出现睁眼困难前患病1至6年。临床特征和电生理检查表明,该疾病是由于睑板前眼轮匝肌异常收缩导致的眼睑痉挛变体。