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2000年和2001年在土耳其分离出的麻疹病毒的基因特征

Genetic characterization of measles viruses isolated in Turkey during 2000 and 2001.

作者信息

Korukluoglu Gulay, Liffick Stephanie, Guris Dalya, Kobune Fumio, Rota Paul A, Bellini William J, Ceylan Ali, Ertem Meliksah

机构信息

National Measles/Rubella Laboratory, Refik Saydam National Hygiene Center, Ankara, Turkey.

出版信息

Virol J. 2005 Jul 19;2:58. doi: 10.1186/1743-422X-2-58.

Abstract

BACKGROUND

Molecular epidemiologic studies have made significant contributions to measles surveillance activities by helping to identify source and transmission pathways of the virus. This report describes the genetic characterization of wild-type measles viruses isolated in Turkey in 2000 and 2001.

RESULTS

Wild-type measles viruses were isolated from 24 cases from five provinces in Turkey during 2001. The viruses were analyzed using the standard genotyping protocols. All isolates were classified as genotype D6, the same genotype that was identified in Turkey in previous outbreaks during 1998.

CONCLUSION

Turkey has begun implementation of a national program to eliminate measles by 2010. Therefore, this baseline genotype data will provide a means to monitor the success of the elimination program.

摘要

背景

分子流行病学研究通过帮助识别病毒的来源和传播途径,为麻疹监测活动做出了重大贡献。本报告描述了2000年和2001年在土耳其分离出的野生型麻疹病毒的基因特征。

结果

2001年期间,从土耳其五个省份的24例病例中分离出野生型麻疹病毒。使用标准基因分型方案对病毒进行了分析。所有分离株均被归类为D6基因型,与1998年土耳其此前疫情中鉴定出的基因型相同。

结论

土耳其已开始实施一项到2010年消除麻疹的国家计划。因此,这些基线基因型数据将提供一种监测消除计划成功与否的方法。

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