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皮肤美白剂综述。

Review of skin-lightening agents.

作者信息

Rendon Marta I, Gaviria Jorge I

机构信息

Department of Dermatology, Dermatology and Aesthetic Center, Boca Raton, Florida 33486, USA.

出版信息

Dermatol Surg. 2005 Jul;31(7 Pt 2):886-9; discussion 889. doi: 10.1111/j.1524-4725.2005.31736.

DOI:10.1111/j.1524-4725.2005.31736
PMID:16029683
Abstract

BACKGROUND

Multiple agents are available for the treatment of hyperpigmentation, a cosmetically important condition seen most often in middle-aged and elderly individuals and resulting from exposure to ultraviolet light, certain drugs or chemicals, or the existence of disease. Many skin-lightening agents cause skin irritation and require months of use before results appear, and some agents are only partly effective.

OBJECTIVE

To help dermatologists make an informed decision when choosing a depigmenting agent.

METHODS

A review of all depigmenting agents used alone and in combination, including its natural properties and information about safety, efficacy, and optimal dosing.

CONCLUSIONS

The speed of efficacy and type and extent of side effects vary greatly among depigmenting agents. Knowing the properties associated with each agent enables a physician to choose a product that will best meet a patient's expectations and minimize adverse reactions.

摘要

背景

有多种药物可用于治疗色素沉着,这是一种在中年人和老年人中最常见的具有重要美容意义的病症,其由暴露于紫外线、某些药物或化学物质或疾病的存在引起。许多美白剂会引起皮肤刺激,且需要数月使用才能见到效果,并且有些药物仅部分有效。

目的

帮助皮肤科医生在选择色素脱失剂时做出明智的决定。

方法

对所有单独使用和联合使用的色素脱失剂进行综述,包括其天然特性以及有关安全性、有效性和最佳剂量的信息。

结论

色素脱失剂在疗效速度以及副作用的类型和程度方面差异很大。了解每种药物的相关特性使医生能够选择最能满足患者期望并使不良反应最小化的产品。

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Review of skin-lightening agents.皮肤美白剂综述。
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Single blind, randomized, controlled trial of a lightening product with and without iontophoresis versus tretinoin and vehicle for hyperpigmentation.一项关于含或不含离子导入法的美白产品与维甲酸及赋形剂治疗色素沉着的单盲、随机、对照试验。
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