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三氯乙酸基质烧灼术治疗嵌甲的疗效

The effectiveness of matrix cauterization with trichloroacetic acid in the treatment of ingrown toenails.

作者信息

Terzi Erdinc, Guvenc Ulas, Türsen Belma, Kaya Tamer İrfan, Erdem Teoman, Türsen Ümit

机构信息

Department of Dermatology, Yenikent State Hospital, Turkey.

Department of Dermatology, Sanliurfa State Hospital, Sanliurfa, Turkey.

出版信息

Indian Dermatol Online J. 2015 Jan-Feb;6(1):4-8. doi: 10.4103/2229-5178.148912.

DOI:10.4103/2229-5178.148912
PMID:25657908
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4314888/
Abstract

Ingrown toenail is an often painful clinical condition that usually affects the big toe. Chemical matricectomy with phenol has a low recurrence rate and good cosmetic results. However, it produces extensive tissue destruction that can result in drainage and delayed healing. Alternatives such as sodium hydroxide and trichloroacetic acid (TCA) have therefore come into vogue. A total of 39 patients with 56 ingrown toenail edges underwent chemical matricectomy with 90% TCA after partial nail avulsion. In most of the patients, adverse effects such as postoperative pain and drainage were minimal. One patient who underwent matricectomy had recurrence in a single nail edge (1.8%) at 12 months follow-up. No recurrence was observed among 38 patients during the mean follow-up period. This was considered to be statistically significant (P < 0.001). Partial nail avulsion followed by TCA matricectomy is a safe, simple, and effective method with low rates of postoperative morbidity and high rates of success.

摘要

嵌甲是一种常伴有疼痛的临床病症,通常累及大脚趾。苯酚化学甲床切除术复发率低且美容效果良好。然而,它会造成广泛的组织破坏,导致引流和愈合延迟。因此,诸如氢氧化钠和三氯乙酸(TCA)等替代方法开始流行起来。共有39例患有56个嵌甲边缘的患者在部分指甲拔除后接受了90% TCA化学甲床切除术。在大多数患者中,术后疼痛和引流等不良反应极小。1例接受甲床切除术的患者在12个月随访时单个指甲边缘复发(1.8%)。在平均随访期内,38例患者未观察到复发。这被认为具有统计学意义(P < 0.001)。部分指甲拔除后行TCA甲床切除术是一种安全、简单且有效的方法,术后发病率低且成功率高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/4314888/9d16aed36afc/IDOJ-6-4-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/4314888/fba10116da3f/IDOJ-6-4-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/4314888/fd8c24dd1984/IDOJ-6-4-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/4314888/524662fdc03c/IDOJ-6-4-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/4314888/9d16aed36afc/IDOJ-6-4-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/4314888/fba10116da3f/IDOJ-6-4-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/4314888/fd8c24dd1984/IDOJ-6-4-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/4314888/524662fdc03c/IDOJ-6-4-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce1d/4314888/9d16aed36afc/IDOJ-6-4-g005.jpg

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本文引用的文献

1
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Dermatol Surg. 2009 Jun;35(6):973-9. doi: 10.1111/j.1524-4725.2009.01165.x. Epub 2009 Apr 8.
2
Comparison of phenol and sodium hydroxide chemical matricectomies for the treatment of ingrowing toenails.苯酚和氢氧化钠化学甲床切除术治疗嵌甲的比较
Dermatol Surg. 2007 Jun;33(6):680-5. doi: 10.1111/j.1524-4725.2007.33143.x.
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A simple, pain-free treatment for ingrown toenails complicated with granulation tissue.一种用于治疗伴有肉芽组织的嵌甲的简单、无痛疗法。
Comparative Efficacy of 10% Sodium Hydroxide, 88% Phenol, and 90% Trichloroacetic Acid as Chemical Cauterants for Partial Matricectomy in the Management of Great Toe Nail Onychocryptosis.
10%氢氧化钠、88%苯酚和90%三氯乙酸作为化学腐蚀剂用于拇趾嵌甲部分甲床切除术的比较疗效
J Cutan Aesthet Surg. 2020 Oct-Dec;13(4):314-318. doi: 10.4103/JCAS.JCAS_183_19.
4
A fast and effective solution for ingrown toenail: Creation of a 2-mm space between tissue and nail by sutureless lateral longitudinal excision.一种快速有效的嵌甲解决方案:通过无缝合的横向纵向切除,在组织和指甲之间创建 2 毫米的空间。
Arch Dermatol Res. 2021 Nov;313(9):799-803. doi: 10.1007/s00403-020-02177-9. Epub 2021 Jan 12.
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Comparison of Chemical Matricectomy with Trichloroacetic Acid, Phenol, or Sodium Hydroxide for Ingrown Toenails: A Systematic Review and Network Meta-Analysis.化学性甲床切除术与三氯乙酸、苯酚或氢氧化钠治疗嵌甲的比较:系统评价和网络荟萃分析。
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Sodium hydroxide chemical matricectomy for the treatment of ingrown toenails: comparison of three different application periods.氢氧化钠化学甲床切除术治疗嵌甲:三种不同应用时间的比较
Dermatol Surg. 2005 Jul;31(7 Pt 1):744-7; discussion 747. doi: 10.1097/00042728-200507000-00002.
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Partial matricectomy with a CO2 laser for ingrown toenail after nail matrix staining.在甲床染色后,使用二氧化碳激光进行部分甲床切除术治疗嵌甲。
Dermatol Surg. 2005 Mar;31(3):302-5. doi: 10.1111/j.1524-4725.2005.31078.
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A surgical approach to ingrown nail: partial matricectomy using CO2 laser.嵌甲的手术治疗方法:使用二氧化碳激光进行部分甲床切除术。
Dermatol Surg. 2002 Jul;28(7):578-80. doi: 10.1046/j.1524-4725.2002.22028.x.
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Recurrent ingrown big toenails are efficiently treated by CO2 laser.复发性嵌甲通过二氧化碳激光可得到有效治疗。
Dermatol Surg. 2002 Jun;28(6):509-12. doi: 10.1046/j.1524-4725.2002.01228.x.
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Treatment of recurrent ingrown great toenail associated with granulation tissue by partial nail avulsion followed by matricectomy with sharpulse carbon dioxide laser.采用部分甲撕脱术,随后用超脉冲二氧化碳激光进行甲床切除术治疗伴有肉芽组织的复发性嵌甲性拇趾。
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