Wang Y, Han X D, Hou Y Y, Chen J X
Reproduction and Immunology Laboratory, Medical School, Nanjing University, Nanjing, China.
Arch Androl. 2005 Jul-Aug;51(4):267-70. doi: 10.1080/014850190923413.
In this study, semen samples from fertile and unexplained infertile men were explored for relationships between seminal plasma immunosuppressive factors (SPIFs), semen pH, liquefaction duration and infection of ureaplasma urealyticum (Uu). SPIFs activity was measured by way of counteracting complement. PH was detected by exact pH test paper. Liquefaction duration was observed at 37 degrees C. The results showed that Uu infection ratios of semen samples with abnormal SPIFs, pH or liquefaction duration were markedly higher than those of normal semen samples. It is suggested that Uu infection decreases the level of SPIFs, changes the pH in semen and prolongs the semen liquefaction so as to cause spermatic quality decline. The enhancement of SPIFs level may change the male body against Uu infection.
在本研究中,对来自可育男性和不明原因不育男性的精液样本进行了探索,以研究精浆免疫抑制因子(SPIFs)、精液pH值、液化时间与解脲脲原体(Uu)感染之间的关系。通过中和补体的方法测定SPIFs活性。用精密pH试纸检测pH值。在37℃观察液化时间。结果显示,SPIFs、pH值或液化时间异常的精液样本中Uu感染率明显高于正常精液样本。提示Uu感染可降低SPIFs水平,改变精液pH值,延长精液液化时间,从而导致精子质量下降。提高SPIFs水平可能改变男性机体对Uu感染的抵抗力。