精索静脉曲张相关性不育中的生殖支原体解脲脲原体感染

Genital Ureaplasma urealyticum infection in varicocele-related infertility.

作者信息

Li H, Guo Y, Wang Y, Sun X

机构信息

Department of Urology, First Teaching Hospital, Beijing Medical University, China.

出版信息

Chin Med J (Engl). 1997 Nov;110(11):865-8.

PMID:9772420

Abstract

OBJECTIVE

To assess the existence of a possible infectious factor in varicocele-related infertility.

METHODS

A total of 925 seminal plasmas from 590 infertile men with varicocele and 335 infertile patients without palpable varicocele were cultured for Ureaplasma urealyticum infection, and routine semen analysis was made.

RESULTS

The infection rate of Ureaplasma urealyticum in seminal plasmas was 48.22%. The asymptomatic genital infection of Ureaplasma urealyticum was traced in 329 (55.76%) varicocele men and 117 (34.93%) infertile patients without varicocele (control group). A significant quantitative difference in the incidence of genital Ureaplasma urealyticum infection between the varicocele and control group was observed (P < 0.005) and asthenozoospermia was significantly more prevalent in the patients with varicocele than in the other patients (P < 0.05).

CONCLUSIONS

Genital Ureaplasma urealyticum infection may play a role in varicocele-related infertility. To prevent future infertility, men with both varicocele and genital Ureaplasma urealyticum infection may benefit from early evaluation and treatment.

摘要

目的

评估精索静脉曲张相关性不育中可能存在的感染因素。

方法

对590例患有精索静脉曲张的不育男性和335例未触及精索静脉曲张的不育患者的925份精液进行解脲脲原体感染培养，并进行常规精液分析。

结果

精液中解脲脲原体的感染率为48.22%。在329例（55.76%）精索静脉曲张男性和117例（34.93%）未患精索静脉曲张的不育患者（对照组）中发现了解脲脲原体无症状生殖器感染。精索静脉曲张组和对照组之间生殖器解脲脲原体感染发生率存在显著的数量差异（P < 0.005），且精索静脉曲张患者中弱精子症的发生率显著高于其他患者（P < 0.05）。