Suarez C R, Black L E, Hurley R M
Department of Pediatrics, Loyola University Medical Center, Maywood, Illinois 60153.
Pediatr Emerg Care. 1992 Apr;8(2):88-90. doi: 10.1097/00006565-199204000-00007.
A five-year-old girl with known sickle cell disease presented with severe hyponatremia and findings compatible with syndrome of inappropriate secretion of antidiuretic hormone (SIADH). She was found to have lead levels in the Class III category. By exclusion, we postulated that the SIADH was in some way related to the high lead levels, since this was the only abnormality the patient exhibited. The toxic lead levels and the elevated vasopressin levels rapidly responded to dimercaprol and calcium EDTA chelation therapy.
一名患有镰状细胞病的5岁女孩出现严重低钠血症，并有与抗利尿激素分泌不当综合征（SIADH）相符的表现。她的铅水平处于III类。通过排除法，我们推测SIADH在某种程度上与高铅水平有关，因为这是该患者唯一表现出的异常。有毒的铅水平和升高的血管加压素水平在使用二巯丙醇和依地酸钙螯合疗法后迅速得到改善。
