椭圆叶藤黄果皮的成分。

Constituents of the pericarp of Garcinia subelliptica.

作者信息

Wu Chien-Chang, Weng Jing-Ru, Won Shen-Jeu, Lin Chun-Nan

机构信息

School of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan 807, Republic of China.

出版信息

J Nat Prod. 2005 Jul;68(7):1125-7. doi: 10.1021/np050084v.

DOI:10.1021/np050084v

PMID:16038565

Abstract

A new benzophenone, garcinielliptone FA (1), and a new benzoylphloroglucinol, garcinielliptone FB (2), along with six known compounds, were isolated from the pericarp of Garcinia subelliptica. The structures and relative configurations of 1 and 2 were elucidated by spectroscopic methods and supported by computer-generated molecular modeling. Compound 2 exhibited cytotoxic activity against several human cancer cell lines.

摘要

从椭圆叶藤黄的果皮中分离出一种新的二苯甲酮——藤黄椭圆酮FA（1）、一种新的苯甲酰基间苯三酚——藤黄椭圆酮FB（2）以及六种已知化合物。通过光谱方法阐明了1和2的结构及相对构型，并得到计算机生成的分子模型的支持。化合物2对几种人类癌细胞系表现出细胞毒性活性。