糙叶金丝桃中的异戊烯基化二苯甲酮和呫吨酮

Prenylated benzophenones and xanthones from Hypericum scabrum.

作者信息

Tanaka Naonobu, Takaishi Yoshihisa, Shikishima Yasuhiro, Nakanishi Yuka, Bastow Kenneth, Lee Kuo-Hsiung, Honda Gisho, Ito Michiho, Takeda Yoshio, Kodzhimatov Olimjon K, Ashurmetov Ozodbek

机构信息

Faculty of Pharmaceutical Sciences, University of Tokushima, Shomachi 1-78, Tokushima 770-8505, Japan.

出版信息

J Nat Prod. 2004 Nov;67(11):1870-5. doi: 10.1021/np040024+.

DOI:10.1021/np040024+

PMID:15568778

Abstract

Two new polyprenylated benzophenones, a new polyprenylated phloroglucinol, and six new xanthone derivatives were isolated from the aerial parts of the Uzbekistan medicinal plant Hypericum scabrum. Their structures were elucidated on the basis of spectroscopic evidence. The isolated compounds showed moderate cytotoxicity for human tumor cells.

摘要

从乌兹别克斯坦药用植物粗糙金丝桃的地上部分分离出两种新的多异戊烯基化二苯甲酮、一种新的多异戊烯基化间苯三酚和六种新的氧杂蒽酮衍生物。基于光谱证据阐明了它们的结构。分离出的化合物对人类肿瘤细胞显示出中等程度的细胞毒性。