甘青青兰根及根茎中的萜类化合物。

Terpenoids from the roots and rhizomes of Nardostachys chinensis.

作者信息

Zhang Yi, Lu Yang, Zhang Li, Zheng Qi-Tai, Xu Li-Zhen, Yang Shi-Lin

机构信息

Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100094, People's Republic of China.

出版信息

J Nat Prod. 2005 Jul;68(7):1131-3. doi: 10.1021/np050125n.

DOI:10.1021/np050125n

PMID:16038567

Abstract

A new diterpene, 10-isopropyl-2,2,6-trimethyl-2,3,4,5-tetrahydronaphtha[1,8-bc]oxocine-5,11-diol (1), and a new monoterpene, 6-hydroxy-7-(hydroxymethyl)-4-methylenehexahydrocyclopenta[c]pyran-1(3H)-one, together with four known sesquiterpenes, delta1(10)-aristolene-9beta-ol, debilon, nardosinone, and kanshone A, were isolated from the roots of Nardostachys chinensis. The structures of the new compounds were established on the basis of their spectroscopic data, and the structure of 1 was confirmed by X-ray crystallographic analysis.

摘要

从甘青青兰的根部分离得到一个新的二萜类化合物10-异丙基-2,2,6-三甲基-2,3,4,5-四氢萘并[1,8-bc]氧杂环辛烷-5,11-二醇（1）、一个新的单萜类化合物6-羟基-7-(羟甲基)-4-亚甲基六氢环戊并[c]吡喃-1(3H)-酮，以及四个已知的倍半萜类化合物δ1(10)-马兜铃烯-9β-醇、去甲木香内酯、nardosinone和甘松酮A。根据新化合物的光谱数据确定了其结构，并通过X射线晶体学分析证实了化合物1的结构。