Cantor A B, Shuster J J
University of Florida, Gainesville 32601.
Stat Med. 1992 May;11(7):931-7. doi: 10.1002/sim.4780110710.
If a patient's failure time is incorrectly recorded as being too early, the correction will lower the plateau of the Kaplan-Meier curve and, hence, the associated estimated cure rate. Implications of this counter-intuitive observation are discussed. In addition, a parametric approach, based on the Gompertz distribution, to the problem of cure rate estimation is presented.
如果患者的失败时间被错误地记录得过早,那么修正后将降低Kaplan-Meier曲线的平台期,从而降低相关的估计治愈率。本文讨论了这一违反直觉的观察结果的影响。此外,还提出了一种基于Gompertz分布的参数化方法来解决治愈率估计问题。