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荨麻水提取物对淋巴细胞增殖的刺激作用及对一氧化氮产生的抑制作用。

Stimulation of lymphocyte proliferation and inhibition of nitric oxide production by aqueous Urtica dioica extract.

作者信息

Harput U Sebnem, Saracoglu Iclal, Ogihara Yukio

机构信息

Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, 06100 Ankara, Turkey.

出版信息

Phytother Res. 2005 Apr;19(4):346-8. doi: 10.1002/ptr.1686.

DOI:10.1002/ptr.1686
PMID:16041733
Abstract

The immunomodulatory and antiinflammatory activities of aqueous Urtica dioica extract were investigated for their effect on the mitogenic response of murine splenocytes and nitric oxide production by murine peritoneal macrophages in vitro. It was found that this extract stimulated the proliferation of T-lymphocytes and suppressed NO production in lipopolysaccharide-stimulated macrophages without affecting cell viability.

摘要

研究了荨麻水提取物的免疫调节和抗炎活性对小鼠脾细胞有丝分裂反应和小鼠腹腔巨噬细胞体外产生一氧化氮的影响。结果发现，该提取物刺激T淋巴细胞增殖，并抑制脂多糖刺激的巨噬细胞中一氧化氮的产生，且不影响细胞活力。

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