Van Citters Gregg W, Lin Henry C
Division of Gastrointestinal and Liver Diseases, Department of Medicine, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, HMR 101, Los Angeles, CA 90033, USA.
Curr Gastroenterol Rep. 2005 Aug;7(4):317-20. doi: 10.1007/s11894-005-0025-x.
Similar to that of all mammals, the human gastrointestinal tract is colonized by 100 trillion bacteria shortly after birth. Remarkably, in the open-tube arrangement of the intestine, this bacterial population is tightly compartmentalized to the distal gut. Contamination of the small intestine with colonic bacterial flora or small intestinal bacterial overgrowth (SIBO) has been understood previously as a complication of uncommon conditions associated with obvious intestinal stasis. However, SIBO has also been found in 78% to 84% of patients with the common condition of irritable bowel syndrome (IBS). In this paper, the diagnostic and treatment approaches to SIBO are reconsidered within the larger framework of the patient with IBS.
与所有哺乳动物一样，人类胃肠道在出生后不久就会被100万亿细菌定植。值得注意的是，在肠道的开放管状结构中，这种细菌群体被紧密分隔在远端肠道。小肠被结肠细菌菌群污染或小肠细菌过度生长（SIBO）以前被认为是与明显肠道淤滞相关的罕见病症的并发症。然而，在肠易激综合征（IBS）这种常见病症的患者中，也发现78%至84%的患者存在SIBO。在本文中，将在IBS患者这个更大的框架内重新审视SIBO的诊断和治疗方法。
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