Burton Allen W, Reddy Suresh K, Shah Hemant N, Tremont-Lukats Ivo, Mendel Ehud
Department of Anesthesiology--Cancer Pain Management, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
J Pain Symptom Manage. 2005 Jul;30(1):87-95. doi: 10.1016/j.jpainsymman.2004.12.011.
We present three cases of severe movement-related spinal pain in patients with advanced metastatic carcinomas successfully treated with percutaneous vertebroplasty (PV). These patients had multi-symptom burden and progressive metastasis. Their movement-related pain was incapacitating and refractory to a variety of more conservative interventions. PV is a minimally invasive technique to stabilize vertebral compression fractures, thereby decreasing spinal pain in this setting. Its use in the setting of advanced cancer with severe movement-related pain has not been previously clarified in the palliative care literature. In summary, PV is a technique with a favorable risk: benefit ratio even in the setting of advanced metastatic cancer. The keys to successful utilization of PV in this patient population are careful patient assessment and selection as outlined in the report, in addition to an experienced care team approach.
我们报告了3例晚期转移性癌患者出现严重的与活动相关的脊柱疼痛，经皮椎体成形术（PV）成功治疗。这些患者有多种症状负担且有进行性转移。他们与活动相关的疼痛使人丧失能力，对多种更保守的干预措施无效。PV是一种稳定椎体压缩性骨折的微创技术，从而在此种情况下减轻脊柱疼痛。在姑息治疗文献中，其在伴有严重与活动相关疼痛的晚期癌症中的应用此前尚未阐明。总之，即使在晚期转移性癌症的情况下，PV也是一种风险效益比良好的技术。在该患者群体中成功应用PV的关键除了报告中概述的仔细的患者评估和选择外，还需要经验丰富的护理团队方法。
