Mansoorinasab Mohamad, Abdolhoseinpour Hesam
Department of Neurosurgery, AJA University of Medical Science, Tehran, Iran.
Department of Neurosurgery, Bou Ali Hospital, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
Interv Med Appl Sci. 2018 Mar;10(1):1-6. doi: 10.1556/1646.10.2018.03.
Vertebral fractures (VFs) are the most usual convolution of metastatic tumors and the vertebral column is the third most ordinary site for painful bone metastases and remains a chief factor of morbidity in cancer patients.
In this paper, we investigated the previous literature on the status of clinical and prospects for the use of percutaneous vertebroplasty (PVP) with polymethylmethacrylate as a remedial alternative for the therapy of refractory pain resulting from malignant vertebral compression and pathologic fractures associated with metastatic tumors of various sites in numerous studies. The scientific document for this remedy, containing safety, immediate and long-term efficacy, and outcome measures, and also the risks of complications, was analyzed in detail.
PVP is a safe, feasible, reliable, effective, and useful procedure, a minimally invasive treatment, and a significant tool for reduction of pain and the relief of pain symptoms.
This method can be employed as a further or narcotic remedy in elected patients. The techniques of PVP present a novel alternative therapy for diverse metastases with potentially large application.
椎体骨折（VFs）是转移性肿瘤最常见的并发症，脊柱是疼痛性骨转移的第三大常见部位，并且仍然是癌症患者发病的主要因素。
在本文中，我们研究了以往关于经皮椎体成形术（PVP）使用聚甲基丙烯酸甲酯作为治疗各种部位转移性肿瘤相关的恶性椎体压缩和病理性骨折所致难治性疼痛的补救替代疗法的临床现状和前景的文献。详细分析了该治疗方法的科学文献，包括安全性、即时和长期疗效、结局指标以及并发症风险。
PVP是一种安全、可行、可靠、有效且有用的手术，是一种微创治疗方法，也是减轻疼痛和缓解疼痛症状的重要手段。
该方法可作为特定患者的进一步治疗或麻醉治疗方法。PVP技术为多种转移瘤提供了一种具有潜在广泛应用的新型替代疗法。
