中枢单胺能系统之间的相互作用：多巴胺 - 血清素。
Interactions between central monoaminergic systems: dopamine-serotonin.
作者信息
Roccatagliata G, Albano C, Cocito L, Maffini M
出版信息
J Neurol Neurosurg Psychiatry. 1979 Dec;42(12):1159-62. doi: 10.1136/jnnp.42.12.1159.
Abstract
Concentration of dopamine and serotonin metabolites (HVA and 5-HIAA) in the CSF was evaluated before and after pharmacological treatment in 19 patients with different neuropsychiatric diseases. In every case a reciprocal modification of the two metabolites occurred after treatment. The result supports the hypothesis of a functional balance between the monoaminergic systems in the central nervous system.
摘要
对19例患有不同神经精神疾病的患者，在药物治疗前后评估了脑脊液中多巴胺和5-羟色胺代谢产物（高香草酸和5-羟吲哚乙酸）的浓度。在每种情况下，治疗后两种代谢产物都出现了相反的变化。该结果支持了中枢神经系统单胺能系统之间存在功能平衡的假说。
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