de Ru J A, Plantinga R F, Majoor M H J M, van Benthem P P G, Slootweg P J, Peeters P H M, Hordijk G J
Department of Otolaryngology - Head and Neck Surgery, University Medical Centre, Utrecht, Netherlands.
B-ENT. 2005;1(2):63-6.
In an evaluation of our patients with parotid gland neoplasms, we noticed that patients with a Warthin's tumour were heavy smokers. The aim of this study was to confirm earlier findings in the literature concerning a possible association between smoking and the development of a Warthin's tumour.
A case control study was performed using the clinical records and discharge letters of all consecutive patients with a Warthin's tumour in the pathology database of our hospital covering the last 15 years. Patients with a pleomorphic adenoma and a group of patients visiting our audiology department were used as controls.
A smoking history was found in 97.5% of the patients with a Warthin's tumour. Of the patients with a pleomorphic adenoma, 59% had a smoking history; 56.5% of the audiology group had a smoking history. Mean age at the time of the operation was 60.1 years of age in the Warthin's tumour group and 48.6 for the pleomorphic adenoma group.
The mean age for the development of a Warthin's tumour is ten years older than for a pleomorphic adenoma. Furthermore, the development seems to be closely related to smoking habits.
在对我们的腮腺肿瘤患者进行评估时，我们注意到沃辛瘤患者是重度吸烟者。本研究的目的是证实文献中关于吸烟与沃辛瘤发生之间可能存在关联的早期发现。
采用病例对照研究，使用我院病理数据库中过去15年所有连续的沃辛瘤患者的临床记录和出院小结。以多形性腺瘤患者和一组到我院听力科就诊的患者作为对照。
97.5%的沃辛瘤患者有吸烟史。多形性腺瘤患者中，59%有吸烟史；听力科就诊组中，56.5%有吸烟史。沃辛瘤组手术时的平均年龄为60.1岁，多形性腺瘤组为48.6岁。
沃辛瘤发生的平均年龄比多形性腺瘤大10岁。此外，其发生似乎与吸烟习惯密切相关。
