van Heyningen C, Watson I D
University Hospital Aintree, Liverpool L9 7AL, UK.
Emerg Med J. 2005 Aug;22(8):599-600. doi: 10.1136/emj.2002.004036.
The use of colchicine, a treatment for acute gout and familial Mediterranean fever, is limited by its toxicity. A relatively low dose of colchicine may be fatal. After a colchicine overdose, monitoring should include 6-12 hourly serum troponin measurements. A rising troponin level predicts cardiovascular collapse and is an indication for more intensive management.
秋水仙碱用于治疗急性痛风和家族性地中海热，但因其毒性而受到限制。相对低剂量的秋水仙碱也可能致命。秋水仙碱过量服用后，监测应包括每6至12小时测量一次血清肌钙蛋白。肌钙蛋白水平升高预示着心血管衰竭，是加强治疗管理的指征。
