• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

对于左侧睾丸有II-III级精索静脉曲张的患者,对其亚临床型右侧精索静脉曲张进行手术是否值得?

Is it worthwhile to operate on subclinical right varicocele in patients with grade II-III varicocele in the left testicle?

作者信息

Pasqualotto Fáibio Firmbach, Lucon Antônio Marmo, de Góes Plínio Moreira, Sobreiro Bernardo Passos, Hallak Jorge, Pasqualotto Eleonora Bedin, Arap Sami

机构信息

University of Caxias do Sul, RS, Brazil.

出版信息

J Assist Reprod Genet. 2005 May;22(5):227-31. doi: 10.1007/s10815-005-4926-2.

DOI:10.1007/s10815-005-4926-2
PMID:16047585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3455497/
Abstract

PURPOSE

To determine whether repair of subclinical varicoceles in the right testicle results in significant seminal improvement in patients with clinical left varicocele.

METHODS

Patients were divided into two groups: Group I (unilateral varicocelectomy) and Group II (bilateral varicocelectomy-subclinical left varicocele). The mean sperm concentration before treatment was higher in Group I (21.01 +/- 19.1) compared to Group II (5.7 +/- 10.7) (p = 0.04).

RESULTS

An increase in volume was detected in the left testicle of patients in Group I (17 +/- 7.9 vs. 22.81 +/- 8.2; p = 0.04) and in the right testicle of patients in Group II (18.4 +/- 6.2 vs. 22.3 +/- 6.5; p = 0.04). Although the mean postoperative sperm concentration in Group I increased slightly (25.7 +/- 22.8), the mean sperm concentration in Group II increased significantly (30.32 +/- 9.8; p = 0.03). Pregnancy rate was higher in Group II (66.7%) compared to Group I (33.3%).

CONCLUSIONS

Even a small, subclinical unrepaired varicocele continues to have a detrimental effect on bilateral testis function in a patient with grade II-III left varicocele.

摘要

目的

确定修复右侧睾丸亚临床型精索静脉曲张是否能使临床左侧精索静脉曲张患者的精液质量得到显著改善。

方法

患者分为两组:第一组(单侧精索静脉结扎术)和第二组(双侧精索静脉结扎术——亚临床型左侧精索静脉曲张)。治疗前,第一组患者的平均精子浓度(21.01±19.1)高于第二组(5.7±10.7)(p = 0.04)。

结果

第一组患者左侧睾丸体积增大(17±7.9对22.81±8.2;p = 0.04),第二组患者右侧睾丸体积增大(18.4±6.2对22.3±6.5;p = 0.04)。虽然第一组术后平均精子浓度略有增加(25.7±22.8),但第二组平均精子浓度显著增加(30.32±9.8;p = 0.03)。第二组的妊娠率(66.7%)高于第一组(33.3%)。

结论

对于患有II - III级左侧精索静脉曲张的患者,即使是微小的、未修复的亚临床型精索静脉曲张也会持续对双侧睾丸功能产生不利影响。

相似文献

1
Is it worthwhile to operate on subclinical right varicocele in patients with grade II-III varicocele in the left testicle?对于左侧睾丸有II-III级精索静脉曲张的患者,对其亚临床型右侧精索静脉曲张进行手术是否值得?
J Assist Reprod Genet. 2005 May;22(5):227-31. doi: 10.1007/s10815-005-4926-2.
2
Bilateral is superior to unilateral varicocelectomy in infertile males with left clinical and right subclinical varicocele: a prospective randomized controlled study.对于患有左侧临床型和右侧亚临床型精索静脉曲张的不育男性,双侧精索静脉曲张切除术优于单侧:一项前瞻性随机对照研究。
Int Urol Nephrol. 2018 Feb;50(2):205-210. doi: 10.1007/s11255-017-1749-x. Epub 2017 Dec 5.
3
The effect of microsurgical varicocelectomy on serum follicle stimulating hormone, testosterone and free testosterone levels in infertile men with varicocele.显微外科精索静脉曲张切除术对精索静脉曲张不育男性血清卵泡刺激素、睾酮及游离睾酮水平的影响
BJU Int. 1999 Dec;84(9):1046-9. doi: 10.1046/j.1464-410x.1999.00353.x.
4
Comparison of bilateral versus unilateral varicocelectomy in men with palpable bilateral varicoceles.双侧可触及精索静脉曲张男性患者双侧与单侧精索静脉结扎术的比较。
J Urol. 1999 Jul;162(1):85-8. doi: 10.1097/00005392-199907000-00021.
5
Testicular growth, sperm concentration, percent motility, and pregnancy outcome after varicocelectomy based on testicular histology.基于睾丸组织学的精索静脉曲张切除术后睾丸生长、精子浓度、活动率百分比及妊娠结局
Fertil Steril. 2005 Feb;83(2):362-6. doi: 10.1016/j.fertnstert.2004.06.067.
6
Semen profile, testicular volume, and hormonal levels in infertile patients with varicoceles compared with fertile men with and without varicoceles.与有或无精索静脉曲张的 fertile 男性相比,精索静脉曲张不育患者的精液参数、睾丸体积和激素水平。 (注:fertile 在此语境下可能表述有误,推测原文想表达的是“有生育能力的”,可根据实际情况修正为“有生育能力的男性” 与“不育男性” 等更准确表述 )
Fertil Steril. 2005 Jan;83(1):74-7. doi: 10.1016/j.fertnstert.2004.06.047.
7
Comparison of testicular volumes before and after varicocelectomy.精索静脉曲张切除术前后睾丸体积的比较。
Urol Int. 1998 Aug;60(4):220-3. doi: 10.1159/000030258.
8
Predictive indicators of successful varicocele repair in men with infertility.不育男性精索静脉曲张修复成功的预测指标。
Int J Fertil Womens Med. 2000 Jul-Aug;45(4):279-84.
9
Effects of subinguinal varicocele ligation on sperm concentration, motility and Kruger morphology.腹股沟下精索静脉曲张结扎术对精子浓度、活力及克鲁格形态的影响。
J Urol. 1997 Nov;158(5):1800-3. doi: 10.1016/s0022-5347(01)64133-8.
10
Efficacy of bilateral and left varicocelectomy in infertile men with left clinical and right subclinical varicoceles: a comparative study.双侧与左侧精索静脉曲张切除术对患有左侧临床型和右侧亚临床型精索静脉曲张的不育男性的疗效:一项对比研究
Urology. 2009 Jun;73(6):1236-40. doi: 10.1016/j.urology.2008.11.050. Epub 2009 Apr 15.

引用本文的文献

1
Current and Future Applications of Artificial Intelligence to Diagnose and Treat Male Infertility.人工智能在男性不育诊断和治疗中的当前及未来应用
Adv Exp Med Biol. 2025;1469:1-23. doi: 10.1007/978-3-031-82990-1_1.
2
Does Varicocele Repair Improve Conventional Semen Parameters? A Meta-Analytic Study of Before-After Data.精索静脉曲张修复术能否改善传统精液参数?一项前后数据的荟萃分析研究。
World J Mens Health. 2024 Jan;42(1):92-132. doi: 10.5534/wjmh.230034. Epub 2023 Jun 22.
3
Are varicoceles the holy grail of Andrology?精索静脉曲张是男科学的圣杯吗?
Int J Impot Res. 2024 May;36(3):177-180. doi: 10.1038/s41443-023-00696-3. Epub 2023 Apr 17.
4
Clinical outcome of pediatric and young adult subclinical varicoceles: a single-institution experience.小儿及青年亚临床精索静脉曲张的临床结局:单机构经验
Asian J Androl. 2021 Nov-Dec;23(6):611-615. doi: 10.4103/aja.aja_22_21.
5
Ultrasound evaluation of varicoceles: systematic literature review and rationale of the ESUR-SPIWG Guidelines and Recommendations.精索静脉曲张的超声评估:系统文献回顾及 ESUR-SPIWG 指南和建议的基本原理。
J Ultrasound. 2020 Dec;23(4):487-507. doi: 10.1007/s40477-020-00509-z. Epub 2020 Jul 27.
6
Cut-off values of the Johnsen score and Copenhagen index as histopathological prognostic factors for postoperative semen quality in selected infertile patients undergoing microsurgical correction of bilateral subclinical varicocele.在接受双侧亚临床精索静脉曲张显微外科矫正的部分不育患者中,Johnsen评分和哥本哈根指数作为术后精液质量组织病理学预后因素的截断值。
Transl Androl Urol. 2019 Aug;8(4):346-355. doi: 10.21037/tau.2019.06.23.
7
It is high time for clinical application of sperm DNA fragmentation testing.精子DNA碎片检测的临床应用时机已经成熟。
Transl Androl Urol. 2017 Sep;6(Suppl 4):S577-S579. doi: 10.21037/tau.2017.06.16.
8
Effects of varicocelectomy on serum testosterone.精索静脉曲张切除术对血清睾酮的影响。
Transl Androl Urol. 2016 Dec;5(6):866-876. doi: 10.21037/tau.2016.08.06.
9
Asymptomatic male currently not desiring fertility with bilateral subclinical varicocele found on ultrasound evaluation and borderline semen analysis results.一名无症状男性,目前不想要孩子,超声检查发现双侧亚临床精索静脉曲张,精液分析结果处于临界状态。
Asian J Androl. 2016 Mar-Apr;18(2):315-6. doi: 10.4103/1008-682X.172645.
10
Asymptomatic postpubertal male with palpable left varicocele and subclinical right varicocele.青春期后无症状男性,左侧精索静脉曲张可触及,右侧为亚临床型精索静脉曲张。
Asian J Androl. 2016 Mar-Apr;18(2):311. doi: 10.4103/1008-682X.169992.

本文引用的文献

1
Induction of spermatogenesis in azoospermic men after varicocele repair.精索静脉曲张修复术后无精子症男性精子发生的诱导。
Hum Reprod. 2003 Jan;18(1):108-12. doi: 10.1093/humrep/deg032.
2
EAU guidelines on male infertility.欧洲泌尿外科学会男性不育症指南。
Eur Urol. 2002 Oct;42(4):313-22. doi: 10.1016/s0302-2838(02)00367-6.
3
Best practice policies for male infertility.男性不育的最佳实践策略。
J Urol. 2002 May;167(5):2138-44.
4
Varicocele--the most common cause of male factor infertility?精索静脉曲张——男性不育因素中最常见的原因?
Hum Reprod Update. 2002 Jan-Feb;8(1):53-8. doi: 10.1093/humupd/8.1.53.
5
Pathophysiology of varicoceles in male infertility.男性不育症中精索静脉曲张的病理生理学
Hum Reprod Update. 2001 Sep-Oct;7(5):473-81. doi: 10.1093/humupd/7.5.473.
6
Varicocelectomy improves intrauterine insemination success rates in men with varicocele.精索静脉曲张切除术可提高患有精索静脉曲张男性的宫内人工授精成功率。
J Urol. 2001 May;165(5):1510-3.
7
Microsurgical varicocelectomy in the era of assisted reproductive technology: influence of initial semen quality on pregnancy rates.辅助生殖技术时代的显微外科精索静脉曲张切除术:初始精液质量对妊娠率的影响。
Fertil Steril. 2001 May;75(5):1013-6. doi: 10.1016/s0015-0282(01)01698-3.
8
Clomiphene citrate versus varicocelectomy in treatment of subclinical varicocele: a prospective randomized study.
Int J Urol. 2001 May;8(5):227-30. doi: 10.1046/j.1442-2042.2001.00289.x.
9
The varicocele dilemma.精索静脉曲张的难题。
Hum Reprod Update. 2001 Jan-Feb;7(1):70-7. doi: 10.1093/humupd/7.1.70.
10
Varicocele treatment in the light of evidence-based andrology.
Hum Reprod Update. 2001 Jan-Feb;7(1):65-9. doi: 10.1093/humupd/7.1.65.