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肾酶,一种来自肾脏的儿茶酚胺代谢激素。

Renalase, a catecholamine-metabolizing hormone from the kidney.

作者信息

Luft Friedrich C

机构信息

Medical Faculty of the Charite, Franz Volhard Clinic, HELIOS Klinikum-Berlin, Max Delbruck Center for Molecular Medicine, Berlin, Germany.

出版信息

Cell Metab. 2005 Jun;1(6):358-60. doi: 10.1016/j.cmet.2005.05.008.

DOI:10.1016/j.cmet.2005.05.008
PMID:16054084
Abstract

A novel flavin adenine dinucleotide-dependent amine oxidase that is secreted by the kidney, circulates in the blood, and modulates cardiac function and systemic blood pressure has recently been discovered. Renalase appears to be a hormone that metabolizes catecholamines, and its discovery will facilitate our understanding of sympathetic regulation.

摘要

最近发现了一种新型的黄素腺嘌呤二核苷酸依赖性胺氧化酶,它由肾脏分泌,在血液中循环,并调节心脏功能和全身血压。肾酶似乎是一种代谢儿茶酚胺的激素,它的发现将有助于我们对交感神经调节的理解。

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Renalase, a catecholamine-metabolizing hormone from the kidney.肾酶,一种来自肾脏的儿茶酚胺代谢激素。
Cell Metab. 2005 Jun;1(6):358-60. doi: 10.1016/j.cmet.2005.05.008.
2
Catecholamines regulate the activity, secretion, and synthesis of renalase.儿茶酚胺调节肾酶的活性、分泌和合成。
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Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure.肾酶是一种新型的可溶性单胺氧化酶,可调节心脏功能和血压。
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Renalase is a novel renal hormone that regulates cardiovascular function.肾酶是一种调节心血管功能的新型肾素。
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Renalase, a catecholamine-metabolising enzyme?肾酶,一种儿茶酚胺代谢酶?
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Sodium-dependent modulation of systemic and urinary renalase expression and activity in the rat remnant kidney.钠依赖性调节大鼠残肾肾酶的系统和尿表达和活性。
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Renalase Protects against Renal Fibrosis by Inhibiting the Activation of the ERK Signaling Pathways.肾酶通过抑制ERK信号通路的激活来预防肾纤维化。
Int J Mol Sci. 2017 Apr 27;18(5):855. doi: 10.3390/ijms18050855.
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Ligand binding phenomena that pertain to the metabolic function of renalase.与肾酶代谢功能相关的配体结合现象。
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Polymorphism of the renalase gene in gestational diabetes mellitus.妊娠期糖尿病患者中肾酶基因的多态性
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Stress and the kidney.压力与肾脏
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Serum renalase is related to catecholamine levels and renal function.血清肾酶与儿茶酚胺水平和肾功能有关。
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