Coe C L, Ershler W B, Champoux M, Olson J
Department of Psychology, University of Wisconsin, Madison 53706.
Ann N Y Acad Sci. 1992 Apr 15;650:276-82. doi: 10.1111/j.1749-6632.1992.tb49136.x.
With increasing age, old animals and humans show decreases in a number of immune responses indicative of the process of immune senescence. Our studies investigated whether social companionship, as a potentially positive psychological intervention, would increase lymphocyte proliferation and natural killer cell activity in the aged nonhuman primate. Contrary to our initial hypothesis, social stimulation resulted in decreased immune responses in old monkeys. With specific modifications of the housing conditions it was possible to prevent these decreases in immune responses from occurring, but social companionship still failed to enhance immune responses in the aged monkey.
随着年龄的增长，老年动物和人类的多种免疫反应会出现下降，这表明了免疫衰老的过程。我们的研究调查了作为一种潜在积极心理干预措施的社交陪伴，是否会增加老年非人灵长类动物的淋巴细胞增殖和自然杀伤细胞活性。与我们最初的假设相反，社交刺激导致老年猴子的免疫反应下降。通过对饲养条件进行特定修改，有可能防止这些免疫反应的下降发生，但社交陪伴仍然未能增强老年猴子的免疫反应。
