Lundberg I, Gustavsson A, Högberg M, Nise G
Department of Occupational Health, Karolinska Hospital, Stockholm, Sweden.
Br J Ind Med. 1992 Jun;49(6):409-15. doi: 10.1136/oem.49.6.409.
The incidence of alcoholism and the incidence of other neuropsychiatric diagnoses were compared between the 767 house painters and the 1212 house carpenters, born in 1925 or later, who were members of the Stockholm branches of their respective trade unions in 1965 and who had been members for at least 10 years before 1970. Four different outcome registers were used: (1) the alcohol crime register, which contained all persons who had broken any law regulating the handling and consumption of alcohol (follow up period 1972-6). (2) The register of diagnoses at early retirement (follow up period 1971-84). (3) The register of diagnoses at discharge from inpatient psychiatric care (follow up period 1968-83). (4) The register of causes of death (follow up period 1965-86). Exposures to solvents and consumption of alcohol were evaluated by interviews with samples of the cohorts. A high average cumulative exposure to solvents was found among the painters. The mean consumption of alcohol was similar in the two cohorts. The incidence of diagnoses of neuropsychiatric disorders was higher in painters than in carpenters in all registers. Alcoholism was the most common neuropsychiatric disorder diagnosed and showed the highest relative risk. The excess of alcoholism among the painters was, however, due singularly to painters who had several registrations in the alcohol crime register or diagnoses of alcoholism in multiple registers. Thus the study implies that excessive alcohol consumption or severe damage due to alcohol, or both, but not less severe problems, were more common in painters than in carpenters. This suggests an interaction between exposure to solvents and intake of alcohol causing an increase in diagnosis of alcoholism among painters.
对767名房屋油漆工和1212名房屋木工的酗酒发病率及其他神经精神疾病诊断发病率进行了比较。这些油漆工和木工出生于1925年或之后,在1965年是各自工会斯德哥尔摩分会的成员,并且在1970年之前已入会至少10年。使用了四种不同的结果登记册:(1)酒精犯罪登记册,其中包含所有违反任何酒精处理和消费管制法律的人员(随访期为1972 - 1976年)。(2)提前退休诊断登记册(随访期为1971 - 1984年)。(3)住院精神科护理出院诊断登记册(随访期为1968 - 1983年)。(4)死亡原因登记册(随访期为1965 - 1986年)。通过对队列样本进行访谈来评估溶剂暴露和酒精消费情况。发现油漆工中溶剂的平均累积暴露量较高。两个队列中的酒精平均消费量相似。在所有登记册中,油漆工的神经精神疾病诊断发病率均高于木工。酗酒是诊断出的最常见神经精神疾病,且相对风险最高。然而,油漆工中酗酒人数过多仅归因于那些在酒精犯罪登记册中有多次记录或在多个登记册中有酗酒诊断的油漆工。因此,该研究表明,过度饮酒或酒精造成的严重损害,或两者兼而有之,但不包括不太严重的问题,在油漆工中比在木工中更为常见。这表明溶剂暴露与酒精摄入之间存在相互作用,导致油漆工中酗酒的诊断增加。