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伊朗儿童和青少年口腔扁平苔藓的患病率:一项为期12年的回顾性研究。

Prevalence of oral lichen planus in Iranian children and adolescents: a 12-year retrospective study.

作者信息

Bakhtiari S, Taheri J B, Toossi P, Azimi S, Kawosi Nezhad Sh

机构信息

Department of Oral Medicine, Dental School, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Dermatology, Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Eur Arch Paediatr Dent. 2017 Dec;18(6):419-422. doi: 10.1007/s40368-017-0315-7. Epub 2017 Nov 14.

Abstract

AIM

To investigate the prevalence of oral lichen planus in patients younger than 18 years, referred to a dermatology centre in Iran during 2002-2014. Lichen planus is a chronic inflammatory, immune-mediated disease that could affect the oral mucosa and is a pre-cancerous condition. The disease usually develops in middle age with female predominance and is rare in children.

METHODS

In this retrospective study, cases with definitive histopathologic diagnosis of lichen planus, over a 12-year period from 2002 to 2014 from a dermatologic hospital archive were evaluated. The prevalence of both cutaneous and oral lichen planus, the male:female ratio and site of involvement were calculated using SPSS version 21.

RESULTS

Thirty-six of 564 patients younger than 18 years old diagnosed with lichen planus. Two females (0.4%) had oral lichen planus. One patient had erosive, and one had bullous, oral lichen planus.

CONCLUSION

Oral lichen planus had a very low frequency in Iranian population younger than 18 years old, identifying these patients is recommended for long-term follow-up.

摘要

目的

调查2002年至2014年期间转诊至伊朗一家皮肤科中心的18岁以下患者中扁平苔藓的患病率。扁平苔藓是一种慢性炎症性、免疫介导的疾病,可累及口腔黏膜,且是一种癌前病变。该疾病通常在中年发病,女性居多,在儿童中罕见。

方法

在这项回顾性研究中,对2002年至2014年这12年间来自一家皮肤科医院档案中确诊为扁平苔藓的病例进行了评估。使用SPSS 21版计算皮肤和口腔扁平苔藓的患病率、男女比例及受累部位。

结果

564名18岁以下被诊断为扁平苔藓的患者中,有36例。两名女性(0.4%)患有口腔扁平苔藓。一名患者患有糜烂性口腔扁平苔藓,一名患有大疱性口腔扁平苔藓。

结论

在伊朗18岁以下人群中,口腔扁平苔藓的发病率非常低,建议对这些患者进行长期随访。

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