Bollen E, den Heyer J C, Tolsma M H, Bellari S, Bos J E, Wintzen A R
Department of Neurology, University Hospital Leiden, The Netherlands.
Brain. 1992 Apr;115 ( Pt 2):445-50. doi: 10.1093/brain/115.2.445.
Smooth pursuit eye movements were studied with infrared reflection equipment in 10 patients with myotonic dystrophy and in 10 age- and sex-matched controls. Smooth pursuit gain, measured after correction for catch-up saccades, was decreased in the patient group. Normal latencies of saccadic eye movements made a lack of attention an unlikely explanation for this low gain. Likewise, presence of catch-up saccades and normal fixation made it unlikely that extra-ocular myopathy explained the low smooth pursuit gain. We suggest that periventricular white matter abnormalities represent a more likely explanation.
采用红外反射设备对10例强直性肌营养不良患者及10例年龄和性别相匹配的对照者进行了平稳跟踪眼球运动研究。校正快速扫视后测得的平稳跟踪增益在患者组中降低。眼球快速运动的正常潜伏期使得注意力不集中不太可能是这种低增益的原因。同样,快速扫视的存在和正常的注视使得眼外肌病不太可能解释平稳跟踪增益低的原因。我们认为脑室周围白质异常更有可能是原因。