Shi G Z
Beijing Institute for Cancer Research.
Zhonghua Yu Fang Yi Xue Za Zhi. 1992 Jan;26(1):13-5.
Sour corn-soybean cake is the main food of the inhabitants in high incidence area of stomach cancer in Linqu county Shandong province. In the extract of the sour corn-soybean cakes, twelve mycotoxin-producing fungi and 3 N-nitrosamines (NDMA, NDEA, NMEA) were detected and the finding rates of the fungi and the N-nitrosamines were 93.3% and 92.3%, respectively; the concentration of NDMA was 0.4-3.8 ng/ml, NDEA 0.2-8.1 ng/ml, and NMEA 0.3-1.4 ng/ml. The positivity rate of the Ames test (most positive materials were direct mutagens) was 44.12%. The experimental results showed that the extract of the sour corn-soybean cakes containing carcinogenic and mutagenic subjects could have some causal relationship with the incidence of stomach cancer.
酸玉米豆饼是山东省临朐县胃癌高发区居民的主要食物。在酸玉米豆饼提取物中，检测到12种产真菌毒素的真菌和3种N-亚硝胺（NDMA、NDEA、NMEA），真菌和N-亚硝胺的检出率分别为93.3%和92.3%；NDMA浓度为0.4 - 3.8 ng/ml，NDEA为0.2 - 8.1 ng/ml，NMEA为0.3 - 1.4 ng/ml。Ames试验阳性率（多数阳性物质为直接诱变剂）为44.12%。实验结果表明，含有致癌和诱变物质的酸玉米豆饼提取物可能与胃癌的发生有一定因果关系。
