Maach L, Gründer H D, Boujija A
Dept. PMC (Ruminants), Rabats-Instituts, Marokko.
Dtsch Tierarztl Wochenschr. 1992 Apr;99(4):133-40.
A total of 120 (80 males and 39 females) newborn Holstein-Frisian calves suffering from acute diarrhoea were studied clinically and biochemically, including the following parameters: pH, pCO2, act. HCO3, BE, RBC, PCV, HV, glucose lactate, urea, creatinine, total bilirubin, total protein, AST, Na, K and Cl. The results were interpreted according to their healthy condition, their age as well as their sex. The study had revealed an extreme metabolic acidosis, haemoconcentration, hypoglycaemia and hypofunction in the kidney and liver. Furthermore, the calves with diarrhoea had showed hyponatraemia, hypochloraemia, and hyperkalaemia. Important correlations between clinical and some blood parameters were found. Metabolic acidosis was more severe in male calves than females. These pathophysiological changes should be put in consideration during the therapy of newborn calves suffering from diarrhoea.
对120头（80头雄性和39头雌性）患有急性腹泻的新生荷斯坦-弗里生犊牛进行了临床和生化研究，包括以下参数：pH值、二氧化碳分压、实际碳酸氢盐、碱剩余、红细胞计数、红细胞压积、血红蛋白、葡萄糖、乳酸、尿素、肌酐、总胆红素、总蛋白、谷草转氨酶、钠、钾和氯。根据犊牛的健康状况、年龄和性别对结果进行了解释。研究发现存在严重的代谢性酸中毒、血液浓缩、低血糖以及肝肾功能减退。此外，腹泻犊牛还出现了低钠血症、低氯血症和高钾血症。发现临床症状与一些血液参数之间存在重要相关性。雄性犊牛的代谢性酸中毒比雌性更严重。在治疗患有腹泻的新生犊牛时，应考虑这些病理生理变化。
