Rommel D, Ragé M, Duprez T, Parent M, Sindic C J M
Department of Neurology, Cliniques universitaires Saint-Luc, B-1200 Brussels, Belgium.
Acta Neurol Belg. 2005 Jun;105(2):89-93.
We describe clinical and magnetic resonance (MR) features in a 69-year-old, Caucasian woman presenting with an unusual meningeal onset of cerebral schistosomiasis. Magnetic resonance work-up demonstrated supra- and infratentorial lesions with prominent brainstem involvement contrasting with the paucisymptomatic clinical presentation. Because of a recent stay in Uganda, including swimming in Lake Victoria, a diagnosis of neuroschistosomiasis was suggested. Serological tests and rectal biopsy confirmed the putative diagnosis. The patient was successfully treated with praziquantel at a dose of 50 mg/kg/day for 15 days. Brain MRI abnormalities improved dramatically within two months.
我们描述了一名69岁的白种女性的临床和磁共振（MR）特征，该患者表现为脑血吸虫病罕见的脑膜起病形式。磁共振检查显示幕上和幕下病变，脑干受累明显，这与症状轻微的临床表现形成对比。由于近期曾在乌干达停留，包括在维多利亚湖游泳，故怀疑为神经血吸虫病。血清学检查和直肠活检证实了初步诊断。患者接受了吡喹酮治疗，剂量为50mg/kg/天，持续15天，治疗成功。脑MRI异常在两个月内显著改善。
