Trinchieri A
Urology Unit, Ospedale A. Manzoni, Via dell'Eremo 9/11, 23800 Lecco, Italy.
Urol Res. 2005 Aug;33(4):247-53. doi: 10.1007/s00240-005-0498-y. Epub 2005 Aug 3.
Idiopathic renal calcium stone disease often presents with reduced bone mineral content. Investigations using non-invasive methods for the measurement of bone mineral content (single and dual-photon absorptiometry, dual-energy x-ray absorptiometry, quantitative computed tomodensitometry) show a slight decrease in skeletal mineral content of idiopathic renal stone formers (RSFs). The alterations in bone mineral content in RSFs have different explanations: prostaglandin-mediated bone resorption, subtle metabolic acidosis and 1-25 vitamin D disorders. Bone mineral content is worsened by insufficient dietary calcium leading to a negative calcium balance.
特发性肾钙结石病常伴有骨矿物质含量降低。使用非侵入性方法测量骨矿物质含量（单光子和双光子吸收测定法、双能X线吸收测定法、定量计算机断层密度测定法）的研究表明，特发性肾结石患者（RSF）的骨骼矿物质含量略有下降。RSF患者骨矿物质含量的改变有不同的解释：前列腺素介导的骨吸收、轻微代谢性酸中毒和1,25-维生素D紊乱。饮食中钙摄入不足导致负钙平衡，会使骨矿物质含量恶化。
