Whitehouse Peter J, Juengst Eric T
Department of Neurology, Case Western Reserve University, Cleveland, Ohio 44120, USA.
J Am Geriatr Soc. 2005 Aug;53(8):1417-22. doi: 10.1111/j.1532-5415.2005.53411.x.
The claim that aging itself is treatable or even preventable has repeatedly been made over the centuries. Antiaging medicine is the current leader of approaches that even claim that geriatrics as a discipline will become increasingly unnecessary. The concept of mild cognitive impairment (MCI) as a condition intermediate between normal cognitive aging and Alzheimer's disease highlights the conceptual and practical difficulty of differentiating aging from disease. What should geriatricians and their organizations make of scientifically mainstream attempts to decelerate, arrest, or compress aspects of the normal human aging, including the brain aging process? This article reviews the political, philosophical, practice-related, and economical implications of antiaging medicine for geriatrics using MCI as a practical example. It concludes by suggesting actions that geriatricians should consider to strengthen their profession and to improve patient care in response to the challenges of longevity medicine.
几个世纪以来,人们不断宣称衰老本身是可以治疗甚至预防的。抗衰老医学是当前各种方法的引领者,这些方法甚至宣称老年医学作为一门学科将越来越没有必要。轻度认知障碍(MCI)这一概念,作为正常认知衰老与阿尔茨海默病之间的一种状态,凸显了区分衰老与疾病在概念和实践上的困难。老年医学专家及其组织应该如何看待那些在科学上主流的、旨在减缓、阻止或压缩正常人类衰老(包括大脑衰老过程)某些方面的尝试呢?本文以MCI为例,综述了抗衰老医学对老年医学在政治、哲学、实践相关及经济方面的影响。文章最后建议老年医学专家应考虑采取行动,以应对长寿医学的挑战,加强其专业领域并改善患者护理。