Whitehouse Peter J, Waller Sara
Department of Neurology, Case Western Reserve University, Cleveland, Ohio, USA.
Neurotherapeutics. 2007 Jul;4(3):560-7. doi: 10.1016/j.nurt.2007.03.003.
Understanding why we produce labels for neuropsychiatric conditions, such as Alzheimer's disease (AD), and how we use those words to tell stories about our brain, as well as which groups control such diagnostic discourse, is important to a wise understanding of our cognitive abilities, their limitations, and even our very human nature. Here, we explore the history and current focus of a newly emerging field called neuroethics and explore its relationship (or lack thereof) to a newly created clinical syndrome called involuntary emotional expressive disorder (IEED). The main argument concerns the lack of neuroethical discussion of issues pertinent to social influences on disease and the construction of professional specialization. We are critical of the processes associated with the creation of both the field and the syndrome, and express concern about their eventual outcomes. The interaction of social, political, and business institutions, the inherent interests of the advancement of larger research projects (and the individuals that compose them), their potential for profit, and other incentives to enhance marketability and public attention toward certain research programs will be examined as we discuss the development of the field of neuroethics. Similarly, we argue that these social factors and forces are instrumental in the development of IEED as a recognizable category and condition. Our critique is guided by the hope that through such analyses we can improve our understanding of how we go about our academic activities in cognitive neuroscience and also improve our efforts to help people suffering from neuropsychiatric conditions, such as dementia.
理解我们为何为神经精神疾病(如阿尔茨海默病,简称AD)生成标签,以及我们如何运用这些词汇讲述关于大脑的故事,还有哪些群体掌控此类诊断话语,对于明智地理解我们的认知能力、其局限性乃至我们的人性而言至关重要。在此,我们探究一个新兴领域——神经伦理学——的历史与当前关注点,并探讨它与一种新创建的临床综合征——非自愿情绪表达障碍(IEED)——之间的关系(或缺乏这种关系)。主要论点涉及神经伦理学对与疾病的社会影响及专业细分构建相关问题缺乏讨论。我们对与该领域和该综合征创建相关的过程持批评态度,并对其最终结果表示担忧。在讨论神经伦理学领域的发展时,我们将审视社会、政治和商业机构的互动、大型研究项目(以及构成这些项目的个人)发展的内在利益、它们的盈利潜力以及其他提高某些研究项目的市场吸引力和公众关注度的激励因素。同样,我们认为这些社会因素和力量在将IEED发展成为一个可识别的类别和病症方面发挥了作用。我们的批评基于这样的希望,即通过此类分析,我们能够增进对我们在认知神经科学领域开展学术活动方式的理解,同时也能改进我们帮助患有神经精神疾病(如痴呆症)的人们的努力。