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精神兴奋剂在广泛性发育障碍中的应用。

The use of psychostimulants in pervasive developmental disorders.

作者信息

Abanilla Patricia Karen, Hannahs Greg A, Wechsler Robyn, Silva Raul R

机构信息

Division of Child and Adolescent Psychiatry, New York University School of Medicine, NY 10016-9196, USA.

出版信息

Psychiatr Q. 2005 Fall;76(3):271-81. doi: 10.1007/s11126-005-2980-7.

DOI:10.1007/s11126-005-2980-7
PMID:16080422
Abstract

Many children with Pervasive Developmental Disorders (PDD) display problematic behaviors similar to those seen in children with Attention Deficit Hyperactivity Disorder (ADHD). This paper will look at the controversy concerning diagnosing comorbid ADHD in children who meet criteria for PDD and review the existing literature examining the efficacy of stimulants in these particular set of behaviors or symptom clusters (hyperactivity, impulsivity and inattention). The potential drawbacks of using stimulants in a population of children and adolescents who exhibit symptoms of PDD and ADHD will be discussed. Finally, this review will also attempt to define potential areas of future research to examine the utility of the psychostimulants in children and adolescents with PDD and symptoms of ADHD.

摘要

许多患有广泛性发育障碍(PDD)的儿童表现出的问题行为与注意力缺陷多动障碍(ADHD)儿童相似。本文将探讨关于诊断符合PDD标准的儿童共病ADHD的争议,并回顾现有文献,这些文献研究了兴奋剂对这些特定行为或症状群(多动、冲动和注意力不集中)的疗效。还将讨论在表现出PDD和ADHD症状的儿童及青少年群体中使用兴奋剂的潜在弊端。最后,本综述还将尝试界定未来研究的潜在领域,以检验精神兴奋剂在患有PDD和ADHD症状的儿童及青少年中的效用。

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The use of psychostimulants in pervasive developmental disorders.精神兴奋剂在广泛性发育障碍中的应用。
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The comorbidity of Pervasive Developmental Disorder and Attention Deficit Hyperactivity Disorder: results of a retrospective chart review.广泛性发育障碍与注意力缺陷多动障碍的共病情况:一项回顾性病历审查结果
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Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.广泛性发育障碍儿童中家长评定的焦虑症状:频率及其与孤独症核心症状和认知功能的关联
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引用本文的文献

1
The effect of stimulants on irritability in autism comorbid with ADHD: a systematic review.兴奋剂对合并注意缺陷多动障碍的自闭症患者易怒情绪的影响:一项系统综述
Neuropsychiatr Dis Treat. 2019 Jun 6;15:1547-1555. doi: 10.2147/NDT.S194022. eCollection 2019.

本文引用的文献

1
The comorbidity of Pervasive Developmental Disorder and Attention Deficit Hyperactivity Disorder: results of a retrospective chart review.广泛性发育障碍与注意力缺陷多动障碍的共病情况:一项回顾性病历审查结果
J Autism Dev Disord. 2004 Jun;34(3):329-39. doi: 10.1023/b:jadd.0000029554.46570.68.
2
Effects of methylphenidate treatment in children with mental retardation and ADHD: individual variation in medication response.哌甲酯治疗智力迟钝和多动症儿童的效果:药物反应的个体差异。
J Am Acad Child Adolesc Psychiatry. 2004 Jun;43(6):686-98. doi: 10.1097/01.chi.0000120024.14101.96.
3
Treatment effects of methylphenidate on cognitive functioning in children with mental retardation and ADHD.
哌甲酯对智力迟钝合并注意力缺陷多动障碍儿童认知功能的治疗效果。
J Am Acad Child Adolesc Psychiatry. 2004 Jun;43(6):677-85. doi: 10.1097/01.chi.0000124461.81324.13.
4
A naturalistic retrospective analysis of psychostimulants in pervasive developmental disorders.广泛性发育障碍中精神兴奋剂的自然主义回顾性分析。
J Child Adolesc Psychopharmacol. 2004 Spring;14(1):49-56. doi: 10.1089/104454604773840481.
5
Methylphenidate treatment in children with borderline IQ and mental retardation: analysis of three aggregated studies.哌醋甲酯治疗边缘智力及智力发育迟缓儿童:三项汇总研究分析
J Child Adolesc Psychopharmacol. 2003 Spring;13(1):29-40. doi: 10.1089/104454603321666171.
6
Treatment effects of methylphenidate on behavioral adjustment in children with mental retardation and ADHD.哌甲酯对智力迟钝和注意力缺陷多动障碍儿童行为调适的治疗效果。
J Am Acad Child Adolesc Psychiatry. 2003 Feb;42(2):209-16. doi: 10.1097/00004583-200302000-00015.
7
How unspecified are disorders of children with a pervasive developmental disorder not otherwise specified? A study of social problems in children with PDD-NOS and ADHD.未另作说明的广泛性发育障碍儿童的病症有多不明确?一项关于未特定型广泛性发育障碍(PDD-NOS)和注意力缺陷多动障碍(ADHD)儿童社会问题的研究。
Eur Child Adolesc Psychiatry. 2000 Sep;9(3):168-79. doi: 10.1007/s007870070040.
8
Efficacy of methylphenidate among children with autism and symptoms of attention-deficit hyperactivity disorder.哌甲酯对患有自闭症及注意力缺陷多动障碍症状儿童的疗效。
J Autism Dev Disord. 2000 Jun;30(3):245-55. doi: 10.1023/a:1005548619694.
9
Differentiating attention-deficit/hyperactivity disorder from pervasive developmental disorder not otherwise specified.将注意力缺陷/多动障碍与未另行指定的广泛性发育障碍相鉴别。
J Learn Disabil. 1998 Nov-Dec;31(6):565-71. doi: 10.1177/002221949803100606.
10
Misdiagnosed ADD/ADHD; rediagnosed PDD.误诊为注意力缺陷多动障碍(ADD/ADHD);重新诊断为广泛性发育障碍(PDD)。
J Am Acad Child Adolesc Psychiatry. 1998 Jan;37(1):113-4. doi: 10.1097/00004583-199801000-00024.