• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

潜在抑制的视觉搜索类似物:对正常和精神分裂症群体中无关刺激加工理论的启示。

The visual search analogue of latent inhibition: implications for theories of irrelevant stimulus processing in normal and schizophrenic groups.

作者信息

Lubow R E, Kaplan Oren

机构信息

Department of Psychology, Tel Aviv University, Ramat Aviv 69978, Israel.

出版信息

Psychon Bull Rev. 2005 Apr;12(2):224-43. doi: 10.3758/bf03196368.

DOI:10.3758/bf03196368
PMID:16082802
Abstract

Latent inhibition (LI) is a robust phenomenon that is demonstrated when a previously inconsequential stimulus is less effective in a new learning situation than a novel stimulus. Despite LI's simplicity, there is considerable disagreement as to its theoretical basis. Attentional theories claim that unattended stimulus preexposures reduce stimulus associability. Alternatively, it has been asserted that associability is unaffected and that LI is a result of competition/retrieval processes. The present article reviews a series of visual search studies, some with normal subjects, both undifferentiated and divided into low and high schizotypals, and others with pathologies that entail dysfunctional attention, such as schizophrenia, Parkinson's disease, and anxiety. The visual search conditions were designed to model those of traditional LI experiments, while tapping attentional processes independently of the learning scores that index LI. A variety of evidence from these and other studies is used to support the involvement of attentional and retrieval processes in LI. A model of the mechanism of action of these processes in LI is presented, together with its application to schizophrenia.

摘要

潜伏抑制(LI)是一种显著的现象,当先前无关紧要的刺激在新的学习情境中比新异刺激的效果更差时就会表现出来。尽管LI很简单,但关于其理论基础仍存在相当大的分歧。注意理论认为,未被注意的刺激预暴露会降低刺激的可关联性。另外,有人认为可关联性不受影响,LI是竞争/提取过程的结果。本文回顾了一系列视觉搜索研究,其中一些研究的对象是正常受试者,包括未分化的以及分为低分裂型人格特质和高分裂型人格特质的受试者,还有一些研究的对象是存在注意力功能障碍的病症患者,如精神分裂症、帕金森病和焦虑症患者。视觉搜索条件旨在模拟传统LI实验的条件,同时独立于指示LI的学习分数来探究注意过程。来自这些研究及其他研究的各种证据被用来支持注意和提取过程在LI中的作用。本文提出了这些过程在LI中的作用机制模型,并阐述了其在精神分裂症中的应用。

相似文献

1
The visual search analogue of latent inhibition: implications for theories of irrelevant stimulus processing in normal and schizophrenic groups.潜在抑制的视觉搜索类似物:对正常和精神分裂症群体中无关刺激加工理论的启示。
Psychon Bull Rev. 2005 Apr;12(2):224-43. doi: 10.3758/bf03196368.
2
Construct validity of the animal latent inhibition model of selective attention deficits in schizophrenia.精神分裂症选择性注意缺陷动物潜伏抑制模型的结构效度。
Schizophr Bull. 2005 Jan;31(1):139-53. doi: 10.1093/schbul/sbi005. Epub 2005 Feb 16.
3
Latent inhibition with a response time measure from a within-subject design: effects of number of preexposures, masking task, context change, and delay.
Neuropsychology. 2001 Apr;15(2):244-53.
4
Clear distinction between preattentive and attentive process in schizophrenia by visual search performance.通过视觉搜索表现明确区分精神分裂症患者的前注意和注意过程。
Psychiatry Res. 2007 Jan 15;149(1-3):25-31. doi: 10.1016/j.psychres.2006.01.014. Epub 2006 Nov 21.
5
Is the attentional dysfunction in schizotypy related to anxiety?
Schizophr Res. 2000 Dec 15;46(2-3):255-67. doi: 10.1016/s0920-9964(00)00021-9.
6
Attentional asymmetry in schizophrenia: disengagement and inhibition of return deficits.精神分裂症中的注意不对称性:脱离与返回抑制缺陷。
Neuropsychology. 2001 Jul;15(3):361-70. doi: 10.1037//0894-4105.15.3.361.
7
Latent inhibition in humans: data, theory, and implications for schizophrenia.
Psychol Bull. 1995 Jan;117(1):87-103. doi: 10.1037/0033-2909.117.1.87.
8
Latent inhibition deficits in high-schizotypal normals: symptom-specific or anxiety-related?
Schizophr Res. 2002 Jan 1;53(1-2):109-21. doi: 10.1016/s0920-9964(01)00166-9.
9
Visual search in schizophrenia: latent inhibition and novel pop-out effects.
Schizophr Res. 2000 Sep 29;45(1-2):145-56. doi: 10.1016/s0920-9964(99)00188-7.
10
Enhancement of latent inhibition in patients with chronic schizophrenia.慢性精神分裂症患者潜在抑制的增强。
Behav Brain Res. 2009 Jan 30;197(1):1-8. doi: 10.1016/j.bbr.2008.08.023. Epub 2008 Aug 28.

引用本文的文献

1
Contextual facilitation: Separable roles of contextual guidance and context suppression in visual search.情境促进:情境引导与情境抑制在视觉搜索中的可分离作用。
Psychon Bull Rev. 2024 Dec;31(6):2672-2680. doi: 10.3758/s13423-024-02508-1. Epub 2024 Apr 30.
2
Reciprocal activation/inactivation of ERK in the amygdala and frontal cortex is correlated with the degree of novelty of an open-field environment.杏仁核和前额叶皮质中细胞外信号调节激酶(ERK)的相互激活/失活与旷场环境的新奇程度相关。
Psychopharmacology (Berl). 2016 Mar;233(5):841-50. doi: 10.1007/s00213-015-4163-z. Epub 2015 Dec 19.
3
Human electrophysiological correlates of learned irrelevance: effects of the muscarinic M1 antagonist biperiden.

本文引用的文献

1
Guided Search 2.0 A revised model of visual search.引导搜索 2.0:一种改进的视觉搜索模型。
Psychon Bull Rev. 1994 Jun;1(2):202-38. doi: 10.3758/BF03200774.
2
Perceptual inhibition of expected inputs: The key that opens closed minds.知觉抑制预期输入:开启封闭思维的关键。
Psychon Bull Rev. 1994 Mar;1(1):56-72. doi: 10.3758/BF03200761.
3
There is a time and a place for everything: bidirectional modulations of latent inhibition by time-induced context differentiation.万物皆有时宜:时间诱导的情境分化对潜伏抑制的双向调节。
人类电生理学与习得性无关的关联:毒蕈碱 M1 拮抗剂苯海索的影响。
Int J Neuropsychopharmacol. 2012 Nov;15(10):1375-85. doi: 10.1017/S1461145711001647. Epub 2011 Nov 18.
4
Dissociating scopolamine-induced disrupted and persistent latent inhibition: stage-dependent effects of glycine and physostigmine.分离东莨菪碱引起的破坏和持久的潜伏抑制:甘氨酸和毒扁豆碱的阶段依赖性效应。
Psychopharmacology (Berl). 2010 Apr;209(2):175-84. doi: 10.1007/s00213-010-1785-z. Epub 2010 Feb 24.
5
The neural underpinnings of associative learning in health and psychosis: how can performance be preserved when brain responses are abnormal?健康和精神病患者联想学习的神经基础:当大脑反应异常时,如何保持表现?
Schizophr Bull. 2010 May;36(3):465-71. doi: 10.1093/schbul/sbq005. Epub 2010 Feb 12.
6
Differential role of muscarinic transmission within the entorhinal cortex and basolateral amygdala in the processing of irrelevant stimuli.乙酰胆堿能传递在內嗅皮層和基底外侧杏仁核中的差異性作用在處理不相關刺激。
Neuropsychopharmacology. 2010 Apr;35(5):1073-82. doi: 10.1038/npp.2009.210. Epub 2010 Jan 13.
7
Functional networks underlying latent inhibition learning in the mouse brain.小鼠大脑中潜在抑制学习的功能网络。
Neuroimage. 2007 Oct 15;38(1):171-83. doi: 10.1016/j.neuroimage.2007.06.031. Epub 2007 Jul 18.
8
Knockdown of Nurr1 in the rat hippocampus: implications to spatial discrimination learning and memory.大鼠海马体中Nurr1基因敲低:对空间辨别学习与记忆的影响
Learn Mem. 2006 Nov-Dec;13(6):734-44. doi: 10.1101/lm.407706.
9
Effects of preexposure and retention interval placement on latent inhibition and perceptual learning in a choice-maze discrimination task.
Learn Behav. 2006 May;34(2):193-201. doi: 10.3758/bf03193194.
10
There is a time and a place for everything: bidirectional modulations of latent inhibition by time-induced context differentiation.万物皆有时宜:时间诱导的情境分化对潜伏抑制的双向调节。
Psychon Bull Rev. 2005 Oct;12(5):806-21. doi: 10.3758/bf03196774.
Psychon Bull Rev. 2005 Oct;12(5):806-21. doi: 10.3758/bf03196774.
4
Construct validity of the animal latent inhibition model of selective attention deficits in schizophrenia.精神分裂症选择性注意缺陷动物潜伏抑制模型的结构效度。
Schizophr Bull. 2005 Jan;31(1):139-53. doi: 10.1093/schbul/sbi005. Epub 2005 Feb 16.
5
Acquired distinctiveness of cues; transfer between discrimination on the basis of familiarity with the stimulus.线索的后天独特性;基于对刺激的熟悉程度在辨别之间的迁移。
J Exp Psychol. 1949 Dec;39(6):770-84. doi: 10.1037/h0058097.
6
The relation between latent inhibition and symptom-types in young schizophrenics.
Behav Brain Res. 2004 Mar 2;149(2):113-22. doi: 10.1016/s0166-4328(03)00221-3.
7
Evidence for impaired visual context processing in schizotypy with thought disorder.思维紊乱的分裂型人格障碍患者视觉情境处理受损的证据。
Schizophr Res. 2004 Jun 1;68(2-3):249-60. doi: 10.1016/S0920-9964(03)00184-1.
8
The interpretation of the measurement of nucleus accumbens dopamine by in vivo dialysis: the kick, the craving or the cognition?通过体内透析测量伏隔核多巴胺的解读:快感、渴望还是认知?
Neurosci Biobehav Rev. 2003 Oct;27(6):527-41. doi: 10.1016/j.neubiorev.2003.09.001.
9
Latent inhibition in human adults without masking.无掩蔽情况下成年人类的潜伏抑制
J Exp Psychol Learn Mem Cogn. 2003 Sep;29(5):1028-40. doi: 10.1037/0278-7393.29.5.1028.
10
Decreased latent inhibition is associated with increased creative achievement in high-functioning individuals.潜在抑制降低与高功能个体的创造性成就增加有关。
J Pers Soc Psychol. 2003 Sep;85(3):499-506. doi: 10.1037/0022-3514.85.3.499.