Carrizo Fernando, Luna Mario A
Department of Pathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Ann Diagn Pathol. 2005 Aug;9(4):189-92. doi: 10.1016/j.anndiagpath.2005.04.019.
We present the cases of 2 pediatric patients with low-grade nasopharyngeal papillary adenocarcinoma with features suggestive of thyroid origin. Both cases showed strong nuclear immunoreactivity for thyroid transcription factor-1 protein and positive immunostaining for cytokeratins 7 and 19. After thyroid imaging studies, local excision was performed in both patients. The patients remain free of disease 2 and 15 years after treatment, with no evidence of lesions in the thyroid or elsewhere.
我们报告了2例患有低度鼻咽乳头状腺癌的儿科患者，其特征提示起源于甲状腺。两例均显示甲状腺转录因子-1蛋白的强核免疫反应性以及细胞角蛋白7和19的免疫染色阳性。经过甲状腺影像学检查后，两名患者均接受了局部切除。治疗后2年和15年，患者均无疾病复发，甲状腺或其他部位均无病变迹象。
