Choung Ho-Kyung, Hwang Jeong-Min
Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Boramae Hospital, Seoul, Korea.
Am J Ophthalmol. 2005 Sep;140(3):433-6. doi: 10.1016/j.ajo.2005.03.047.
To determine the effect of Surgi Wrap (MacroPore Biosurgery, Inc, San Diego, California, USA) in delayed adjustable strabismus surgery.
An animal study.
A prospective, masked-observer, controlled study was performed in rabbits. Forty-eight eyes of 24 rabbits were divided into two groups. After recession of the superior rectus muscle (SRM), Surgi Wrap was applied beneath and over the SRM in the Surgi Wrap group, and no barrier was applied in the control group. Delayed adjustment was performed once on each superior rectus muscle at 1, 2, and 3 weeks after surgery by a masked observer. The possible length to adjust, the force required for the adjustment, and the degree of any adhesions were also evaluated.
In the control group, adjustment was impossible in all of the five eyes at 1, 2, and 3 postoperative weeks, respectively. In the Surgi Wrap group, adjustment was possible in four of 10 eyes at 1 week after surgery, in two of 10 eyes at 2 weeks after surgery, and in none of the 10 eyes at 3 weeks after surgery.
The use of Surgi Wrap could delay adjustment in some of the eyes up to 1 or 2 weeks after surgery. Surgi Wrap could be helpful for short-term delayed adjustment in rabbit eyes.
确定Surgi Wrap(美国加利福尼亚州圣地亚哥的MacroPore生物外科公司)在延迟可调斜视手术中的效果。
一项动物研究。
对兔子进行前瞻性、双盲观察者对照研究。将24只兔子的48只眼分为两组。在直肌后退术后,Surgi Wrap组在直肌下方和上方应用Surgi Wrap,对照组不应用屏障物。术后1周、2周和3周,由双盲观察者对每只直肌进行一次延迟调整。还评估了可能的调整长度、调整所需的力以及任何粘连的程度。
对照组中,术后1周、2周和3周时,所有五只眼中均无法进行调整。在Surgi Wrap组中,术后1周时10只眼中有4只可以调整,术后2周时10只眼中有2只可以调整,术后3周时10只眼中无一可以调整。
使用Surgi Wrap可使部分眼睛在术后长达1或2周的时间内延迟调整。Surgi Wrap可能有助于兔眼的短期延迟调整。